Lasofoxifene Tartrate CAS 190791-29-8 Chiral Dị Ọcha ≥99.0% Ịdị Ọcha ≥98.0% (HPLC) API Ịdị Ọcha Dị Elu
Onye nrụpụta nwere ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha Chemical: Lasofoxifene Tartrate
OZI: 190791-29-8
Lasofoxifene Tartrate (CAS: 190791-29-8) na ọgwụgwọ nke Postmenopausal Osteoporosis
Aha Chemical | Lasofoxifene Tartrate |
Ụdị okwu | (5R,6S) -5,6,7,8-Tetrahydro-6-phenyl-5-[4-[2- (1-pyrrolidinyl) ethoxy] phenyl] -2-naphthalenol Tartrate Oporia |
Nọmba CAS | 190791-29-8 |
Nọmba CAT | RF-API20 |
Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms |
Usoro ihe omimi | C28H31NO2.ClH |
Ibu molekụla | 450.019 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ |
Mmiri (KF) | ≤0.50% |
Ọla dị arọ | ≤20ppm |
Chiral ịdị ọcha | ≥99.0% |
Ụzọ ịdị ọcha / nyocha | ≥98.0% (HPLC) |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.50% |
Nlele ọkọlọtọ | Ndị China Pharmacopoeia (CP);Standardkpụrụ ụlọ ọrụ |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API);Osteoporosis postmenopausal |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Lasofoxifene Tartrate (CAS: 190791-29-8) nwere àgwà dị elu.
Lasofoxifene Tartrate bụ ọgbọ nke atọ, na-abụghị steroidal selective estrogen receptor modulator (SERM).Ọ na-ahọrọ ejikọta na ERalpha mmadụ nwere uru IC50 nke 1.5 nM ma na-egbochi ọkpụkpụ ọkpụkpụ na oke ovariectomized.Na nyocha ụlọ ọgwụ nke osteoporosis postmenopausal, 0.5 mg / ụbọchị lasofoxifene jikọtara ya na mbelata ihe ize ndụ nke mgbaji ndị na-abụghị vertebral na vertebral, ER-positive cancer cancer, ọrịa obi obi, na ọrịa strok mana ihe ize ndụ dị ukwuu nke ihe omume thromboembolic venous.E gosikwara Lasofoxifene ka ọ na-eme ihe dị ka agonist na-agbanwe agbanwe na CB2 cannabinoid onye na-anabata ya, na-egosi na ọ nwere ike ịmeghachi ya dị ka ọgwụgwọ maka ihe ngosi ebe CB2 bụ ihe mgbaru ọsọ.