Lenvatinib Mesylate Intermediate CAS 15568-85-1 Dị Ọcha> Ụlọ ọrụ 97.0% (HPLC)
Ruifu Chemical Supply Lenvatinib Mesylate Intermediates nwere ịdị ọcha dị elu
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4
Aha Chemical | 5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion. |
Ụdị okwu | 5- (Methoxymethylene) Acid Meldrum;Cabozantinib adịghị ọcha 56;Lenvatinib adịghị ọcha 79 |
Nọmba CAS | 15568-85-1 |
Nọmba CAT | RF-PI1967 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C8H10O5 |
Ibu molekụla | 186.16 |
Ebe Na-agbaze | 132.0 ~ 134.0 ℃ |
Njupụta | 1.297±0.06 g/cm3 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ odo |
1 H NMR Spectrum | Nkwekọrịta na Ọdịdị |
Ụzọ ịdị ọcha / nyocha | > 97.0% (HPLC) |
Mgbakọta adịghị ọcha | <3.00% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ndị etiti Lenvatinib Mesylate (CAS: 857890-39-2) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
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5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione (CAS: 15568-85-1) bụ etiti nke Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib bụ ọgwụ cancer thyroid nke Eisai Corporation nke Japan mepụtara (koodu: E7080), bụ nke onye na-emechi ọnụ nke tyrosine kinase (RTK) nke na-emechi ọnụ ma nwee ike igbochi ọrụ kinase nke vascular endothelial growth factor (VEGF) ndị na-anabata VEGFR1. FLT1), VEGFR2 (KDR), na VEGFR3 (FLT4).Lenvatinib nwekwara ike igbochi itinye aka nke RTK ndị ọzọ na angiogenesis pathological, uto tumor, na ọganihu cancer ma e wezụga maka ọrụ cellular ha na-emekarị gụnyere fibroblast growth factor (FGF) ndị na-anabata FGFR1, 2, 3, na 4;ihe nnabata ihe uto nke platelet (PDGFR [alpha]), KIT, na RET.[Ngosipụta]: Lenvatinib dị mma maka ọgwụgwọ ndị ọrịa nke ọrịa cancer thyroid nke nlọghachi azụ mpaghara ma ọ bụ ụdị metastasis, ụdị ọganihu na redioactive iodine-refractory dị iche iche.Na February 13, 2015, US FDA kwadoro ọgwụ anticancer Lenvatinib maka ọgwụgwọ ọrịa cancer thyroid.Lenvatinib bụ onye na-egbochi enzyme multi-ezubere iche, na-enwe ike igbochi VEGFR2 na VEGFR3 (vaskụla endothelial growth factor receptor).Aha ahia nke Lenvatinib bụ Lenvima.Na May 20, 2015, Ụlọ Ọrụ Na-ahụ Maka Ọgwụ na Europe (EMA) kwadoro Lenvatinib maka ọgwụgwọ nke mkparị, nke dị na mpaghara ma ọ bụ metastatic dị iche iche (papillary, follicular, Hurthle ụdị) ọrịa cancer thyroid (DTC).N'ime ule ahụ, oge ndụ nke etiti maka ndị ọrịa nwere redioactive iodine refractory DTC nke a na-emeso Lenvatinib bụ ọnwa 18 ebe uru maka ndị ọrịa na-ewere placebo bụ nanị ọnwa 3.
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Lenvatinib Mesylate Intermediate CAS 15568-85-1...
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Lenvatinib Mesylate CAS 857890-39-2 Assay 98.0 ~...
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Desquinolinyl Lenvatinib CAS 796848-79-8 Ịdị ọcha...
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4-Amino-3-Chlorophenol CAS 17609-80-2 Lenvatini...
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4-Amino-3-Chlorophenol Hydrochloride CAS 52671-...
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4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 4...
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Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8...
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Lenvatinib Mesylate Intermediate CAS 205448-65-...
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Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylat...