Lenvatinib Mesylate Intermediate CAS 205448-65-3 Ịdị Ọcha>98.0% (HPLC) Foto egosipụtara

Lenvatinib Mesylate Intermediate CAS 205448-65-3 Ịdị ọcha> Ụlọ ọrụ 98.0% (HPLC)

Nkọwa dị mkpirikpi:

Aha Kemịkal: Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate

CAS: 205448-65-3

Dị ọcha:> 98.0% (HPLC)

Ọdịdị: Gbanyụọ-Ọcha ruo ntụ ntụ edo edo

Ọkara nke Lenvatinib Mesylate CAS 857890-39-2

E-Mail: alvin@ruifuchem.com

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Nkọwa:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates nwere ịdị ọcha dị elu
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1- (2-Chloro-4-Hydroxyphenyl) -3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5- (Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dion CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Njirimara kemịkalụ:

Aha Chemical	Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate
Ụdị okwu	1,4-Dihydro-7-Methoxy-4-Oxo-6-Quinolinecarboxylic Acid Methyl Ester;7-Methoxy-4-Oxo-1,4-Dihydro-Quinoline-6-Carboxylic Acid Methyl Ester;Ọkara Lenvatinib 3
Nọmba CAS	205448-65-3
Nọmba CAT	RF-PI1973
Ọnọdụ Ahịa	N'ahịa, Ikike Mmepụta 50 MT/Afọ
Usoro ihe omimi	C12H11NO4
Ibu molekụla	233.22
Ebe esi nri	421.0± 45.0 ℃
Njupụta	1.267±0.060 g/cm3
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Gbanyụọ-Ọcha ruo ntụ ntụ edo edo
Ụzọ ịdị ọcha / nyocha	> 98.0% (HPLC)
Ọnwụ na ihicha	<1.00%
Ihe fọdụrụ na mgbanye	<0.50%
Mgbakọta adịghị ọcha	<2.00%
H-NMR	Dabara na Ọdịdị
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Ndị na-ahụ maka ọgwụ

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Uru:

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Ngwa:

Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate (CAS: 205448-65-3) bụ etiti nke Lenvatinib Mesylate (CAS: 857890-39-2).Lenvatinib, nke a na-ere n'okpuru aha aha Lenvima n'etiti ndị ọzọ, bụ ọgwụ na-egbochi ọrịa cancer maka ọgwụgwọ ụfọdụ ụdị ọrịa cancer thyroid yana maka ọrịa cancer ndị ọzọ.Emepụtara ya bụ Eisai Co. ma na-eme dị ka onye na-egbochi ọtụtụ kinase megide VEGFR1, VEGFR2 na VEGFR3 kinases.A kwadoro Lenvatinib (ebe ọ bụ na 2015) maka ọgwụgwọ ọrịa cancer thyroid dị iche iche nke na-emeghachi ugboro ugboro ma ọ bụ metastatic, na-aga n'ihu, na-anabataghị ọgwụgwọ na radioactive iodine (radioiodine).Na May 2016, US Food and Drug Administration (FDA) kwadoro ya (na njikọ ya na everolimus) maka ọgwụgwọ nke carcinoma renal cell carcinoma na-esote otu tupu ọgwụgwọ angiogenic.A kwadokwara ọgwụ ahụ na US na na European Union maka hepatocellular carcinoma nke enweghị ike iwepụ n'ịwa ahụ na ndị ọrịa na-enwetabeghị ọgwụgwọ ọrịa kansa site n'ọnụ ma ọ bụ ntụtụ.