Linagliptin CAS 668270-12-0 ịdị ọcha ≥99.0% (HPLC) ụlọ ọrụ

Nkọwa dị mkpirikpi:

Aha ọgwụ: Linagliptin

Nọmba ekwentị: 668270-12-0

Dị ọcha: ≥99.0% (HPLC)

Ọdịdị: White ma ọ bụ Gbanyụọ-White Crystalline Powder

Linagliptin maka ọgwụgwọ ụdị ọrịa shuga mellitus nke II

API, Ogo dị elu, mmepụta azụmahịa

E-Mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Onye na-emepụta ihe, ịdị ọcha dị elu, mmepụta azụmahịa
Aha ọgwụ: Linagliptin
Nọmba ekwentị: 668270-12-0

Njirimara kemịkalụ:

Aha Chemical Linagliptin
Ụdị okwu BI-1356;8-[(3R) -3-Amino-1-piperidinyl] -7- (2-butynyl) -3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl) methyl]-1H -Purine-2,6-dione
Nọmba CAS 668270-12-0
Nọmba CAT RF-API105
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C25H28N8O2
Ibu molekụla 472.54
Ebe Na-agbaze 197.0 ruo 200.0 ℃
Solubility Soluble na DMSO
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ntụ ntụ kristal na-acha ọcha ma ọ bụ gbanyụọ
NMR Nkwekọrịta na Ọdịdị
Ụzọ ịdị ọcha / nyocha ≥99.0% (HPLC)
Ọnwụ na ihicha ≤0.50%
Ihe fọdụrụ na mgbanye ≤0.10%
Ọla dị arọ ≤10ppm
Ihe ndị emetụtara  
Otu adịghị ọcha ≤0.50%
Mgbakọta adịghị ọcha ≤1.0%
Isomer ≤0.15%
Ihe mgbaze fọdụrụnụ  
Methanol ≤3000ppm
Isopropanol ≤5000ppm
DMF ≤800ppm
Dichloromethane ≤600ppm
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji API

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.

Uru:

1

Ajụjụ:

Ngwa:

Linagliptin (CAS: 668270-12-0) bụ ihe mgbochi DPP-4 nke Boehringer Ingelheim mepụtara maka ọgwụgwọ ụdị ọrịa shuga II.Njirimara ọgwụ abụọ na-ekewa linagliptin dị iche na ndị na-egbochi DPP-4 ndị ọzọ bụ na ọ nwere profaịlụ ọgwụ na-abụghị linear na usoro akụrụ anaghị ewepụ ya.Linagliptin (otu oge kwa ụbọchị) bụ ndị US FDA kwadoro na 2 Mee 2011 maka ọgwụgwọ ụdị ọrịa shuga II.Boehringer Ingelheim na Lilly na-ere ya.Linagliptin, rere n'okpuru akara aha Tradjenta n'etiti ndị ọzọ.A na-eji ya na mgbatị ahụ na nri.

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