Linagliptin CAS 668270-12-0 ịdị ọcha ≥99.0% (HPLC) ụlọ ọrụ
Onye na-emepụta ihe, ịdị ọcha dị elu, mmepụta azụmahịa
Aha ọgwụ: Linagliptin
Nọmba ekwentị: 668270-12-0
Aha Chemical | Linagliptin |
Ụdị okwu | BI-1356;8-[(3R) -3-Amino-1-piperidinyl] -7- (2-butynyl) -3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl) methyl]-1H -Purine-2,6-dione |
Nọmba CAS | 668270-12-0 |
Nọmba CAT | RF-API105 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C25H28N8O2 |
Ibu molekụla | 472.54 |
Ebe Na-agbaze | 197.0 ruo 200.0 ℃ |
Solubility | Soluble na DMSO |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha ọcha ma ọ bụ gbanyụọ |
NMR | Nkwekọrịta na Ọdịdị |
Ụzọ ịdị ọcha / nyocha | ≥99.0% (HPLC) |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.10% |
Ọla dị arọ | ≤10ppm |
Ihe ndị emetụtara | |
Otu adịghị ọcha | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.0% |
Isomer | ≤0.15% |
Ihe mgbaze fọdụrụnụ | |
Methanol | ≤3000ppm |
Isopropanol | ≤5000ppm |
DMF | ≤800ppm |
Dichloromethane | ≤600ppm |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | API |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Linagliptin (CAS: 668270-12-0) bụ ihe mgbochi DPP-4 nke Boehringer Ingelheim mepụtara maka ọgwụgwọ ụdị ọrịa shuga II.Njirimara ọgwụ abụọ na-ekewa linagliptin dị iche na ndị na-egbochi DPP-4 ndị ọzọ bụ na ọ nwere profaịlụ ọgwụ na-abụghị linear na usoro akụrụ anaghị ewepụ ya.Linagliptin (otu oge kwa ụbọchị) bụ ndị US FDA kwadoro na 2 Mee 2011 maka ọgwụgwọ ụdị ọrịa shuga II.Boehringer Ingelheim na Lilly na-ere ya.Linagliptin, rere n'okpuru akara aha Tradjenta n'etiti ndị ọzọ.A na-eji ya na mgbatị ahụ na nri.