Luliconazole CAS 187164-19-8 Dị Ọcha ≥99.0% HPLC Factory API Ogo dị elu
Nyefee Luliconazole na ihe ndị metụtara ya
Luliconazole CAS 187164-19-8
(1-Imidazolyl) acetonitrile CAS 98873-55-3
(S) -2,4-Dichloro-α-(Chloromethyl) benzyl Mmanya CAS 126534-31-4
| Aha Chemical | Luliconazole |
| Ụdị okwu | (2E) -2- [(4R) -4- (2,4-Dichlorophenyl) -1,3-dithiolan-2-ylidene] -2- (1H-imidazol-1-yl) acetonitrile;NND 502 |
| Nọmba CAS | 187164-19-8 |
| Nọmba CAT | RF-API110 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C14H9Cl2N3S2 |
| Ibu molekụla | 354.27 |
| Ebe Na-agbaze | 150.0 ka 154.0 ℃ |
| Ntụgharị a kapịrị ọnụ [a]20/D | -48.0° ruo -53.0° (C=1, DMF) |
| Solubility | Na-adịghị edozi na Mmiri;Soluble na acetone;Soluble ntakịrị na methanol |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Gbanyụọ-Ọcha ka ọ dị ọkụ kristal ntụ ntụ |
| njirimara IR | Ụdị infrared nke ihe nlele kwesịrị ikwekọ na nke ọkọlọtọ ntụaka |
| njirimara HPLC | Oge njide nke isi ọnụ ọgụgụ kachasị elu nke ngwọta nlele kwesịrị ikwekọ na nke ọkọlọtọ ọkọlọtọ dị ka enwetara na ule |
| Ọnwụ na ihicha | ≤0.50% |
| Ihe fọdụrụ na mgbanye | ≤0.20% |
| Ọla dị arọ (Pb) | ≤20ppm |
| Ihe ndị emetụtara | |
| Ọdịghị ọcha nke Onye ọ bụla | ≤0.20% |
| Mgbakọta adịghị ọcha | ≤0.50% |
| Ihe mgbaze fọdụrụnụ | |
| Methanol | ≤3000ppm |
| Acetonitrile | ≤410ppm |
| Dichloromethane | ≤600ppm |
| N-Hexane | ≤290ppm |
| Ethyl acetate | ≤5000ppm |
| Tetrahydrofuran | ≤720ppm |
| Methyl tert-Butyl Ether | ≤5000ppm |
| N-Heptane | ≤5000ppm |
| Triethylamine | ≤320ppm |
| Dimethyl sulfoxide | ≤5000ppm |
| Ụzọ ịdị ọcha / nyocha | ≥99.0% (HPLC) (na nke a mịrị amị) |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ndị na-ahụ maka ọgwụ |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Luliconazole (CAS: 187164-19-8) bụ ọgwụ nje antifungal imidazole nke dị n'elu nwere nnukwu ụdịdị dị iche iche yana ọrụ antifungal siri ike.Luliconazole bụ ụdị analog nke lanoconazole.Ọ nwere ike igbochi njikọ mgbidi cell fungal yana uto fungal site na ibelata ọkwa ergosterol site na igbochi ọrụ lanosterol demethylase.Ewezuga iji ya maka ọgwụgwọ ụkwụ onye na-eme egwuregwu, itching na mgbanaka, emebekwara ya maka ọgwụgwọ onychomycosis (nail fungus) ma ugbu a abanyekwala n'usoro ahụike nke III.Ụlọ ọrụ Japanese pesticide Corporation (NihonNohyaku Co., Ltd.) mepụtara ngwaahịa a na mbụ.Na Nọvemba 2013, FDA akwadola ude luliconazole 1% maka ịbanye n'ahịa maka ọgwụgwọ n'elu nke ụkwụ ndị na-eme egwuregwu interdigital, jock itching na ringworm na aha ahia bụ Luzu wee banye n'ahịa na North America.N'ihe dị ka Eprel 2005, a kwadoro luliconazole ịbanye n'ahịa na Japan n'okpuru aha ahia Lulicon.Na Jenụwarị 2010 na June 2012, akwadoro ya maka ire ahịa na India na China n'otu n'otu.
