Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Dị Ọcha>99.0% (HPLC) Nintedanib Esylate Intermediate Factory egosipụtara

Methyl 2-Oxoindoline-6-Carboxylate CAS 14192-26-8 Dị Ọcha>99.0% (HPLC) Nintedanib Esylate Factory Intermediate Factory

Nkọwa dị mkpirikpi:

Aha Chemical: Methyl 2-Oxoindoline-6-Carboxylate

OZI: 14192-26-8

Dị ọcha:> 99.0% (HPLC)

Ọdịdị: Ìhè Yellow ruo Brown ntụ ntụ

N'etiti Nintedanib Esylate (CAS: 656247-18-6) na ọgwụgwọ ọrịa cancer akpa ume na-abụghị obere cell & idiopathic pulmonary fibrosis (IPF)

Ogo dị elu, mmepụta azụmahịa

E-Mail: alvin@ruifuchem.com

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) nwere àgwà dị elu, mmepụta azụmahịa.

Njirimara kemịkalụ:

Aha Chemical	Methyl 2-Oxoindoline-6-Carboxylate
Ụdị okwu	2-Oxoindoline-6-Carboxylic Acid Methyl Ester;Methyl Oxindole-6-Carboxylate
Nọmba CAS	14192-26-8
Nọmba CAT	RF-PI1524
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C10H9NO3
Ibu molekụla	191.19
Ebe Na-agbaze	184.0 ~ 190.0 ℃
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Agba odo na ntụ ntụ ntụ ntụ
1 H NMR Spectrum	Nkwekọrịta na Ọdịdị
Ụzọ ịdị ọcha / nyocha	> 99.0% (HPLC)
Ọnwụ na ihicha	<1.00%
Mgbakọta adịghị ọcha	<1.00%
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Ọkara nke Nintedanib Esylate (CAS: 656247-18-6)

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) Ụzọ sịntetik

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.

Uru:

Ajụjụ:

Ngwa:

Methyl 2-Oxoindoline-6-Carboxylate (CAS: 14192-26-8) bụ ihe etiti eji akwado Nintedanib Esylate (CAS: 656247-18-6).Nintedanib Esylate bụ ihe na-eme ihe ike, ọnụ nke angiokinase atọ nke Boehringer Ingelheim mepụtara nke na-elekwasị anya ụzọ proangiogenic na pro-fibrotic ụzọ ndị na-anabata vaskụla endothelial growth factor receptor, fibroblast growth factor receptor na platelet enwetara uto nke ezinụlọ nnata, yana Src na Flt-3. kinases.A kwadoro Nintedanib Esylate maka ọgwụgwọ nke idiopathic pulmonary fibrosis (IPF), ọnọdụ nke ngụgụ na-eji nwayọọ nwayọọ na-afụ ụfụ ka oge na-aga, site na US FDA na October 2014 na EMA na January 2015. FDA nyere nintedanib esylate ngwa ngwa. , nlebanya mbụ, ngwaahịa nwa mgbei, na nhọpụta nhọpụta.EMA kwadoro ya na Nọvemba 2014 maka ọgwụgwọ ọrịa cancer akpa ume na-abụghị obere cell yana docetaxel mgbe usoro ọgwụgwọ mbụ gasịrị.