N-Acetyl-L-Cysteine CAS 616-91-1 (Ac-Cys-OH; NAC) Nyocha 98.5 ~ 101.0% Ụlọ ọrụ dị elu
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta ihe na onye na-ebubata N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) nwere oke mma.Ruifu Chemical na-enye usoro amino asịd na ihe mpụta.N'ihi àgwà ngwaahịa anyị magburu onwe ya, ọnụ ahịa ezi uche dị na ya, anyị nwetara aha ọma yana ntụkwasị obi site n'aka ndị ahịa anyị n'ụlọ na ná mba ọzọ.Anyị nwere ike ịnye COA, nnyefe zuru ụwa ọnụ, obere na nnukwu ọnụọgụ dị.Ọ bụrụ na ị nwere mmasị na N-Acetyl-L-Cysteine ,Please contact: alvin@ruifuchem.com
| Aha Chemical | N-Acetyl-L-Cysteine |
| Ụdị okwu | Ac-Cys-OH;acetylcysteine;NAC;LNAC;N-Acetylcysteine ;N-Acetyl-3-Mercaptoalanine;Acetyl-Laevo-Cysteine |
| Ọnọdụ Ahịa | N'ahịa, Ikike Mmepụta Tọn 50 kwa ọnwa |
| Nọmba CAS | 616-91-1 |
| Usoro ihe omimi | C5H9NO3S |
| Ibu molekụla | 163.19 |
| Ebe Na-agbaze | 106.0 ~ 108.0 ℃ (ọkụ) |
| Mmetụta | Mmetụta ikuku |
| Mmiri Solubility | Soluble n'ime mmiri, ihe fọrọ nke nta ka ọ bụrụ nghọta |
| Solubility | Soluble na ethanol, methanol, mmanya.Ihe na-adịghị mma na Ether |
| Okpomọkụ nchekwa. | Edechiri ya na nkụ, na-echekwa na okpomọkụ ụlọ |
| COA & MSDS | Dị |
| Nhazi | Amino Acids & Mwepụta |
| Ụdị | Ruifu Chemical |
| Nkwupụta ihe egwu | 36/37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ. |
| Nkwupụta nchekwa | S22 - Ekula uzuzu.S24/25 - Zere kọntaktị na akpụkpọ ahụ na anya. |
| WGK Germany | 3 |
| RTECS | HA 1660000 |
| F | 10-23 |
| TSCA | Ee |
| Koodu HS | 2922491990 |
| Ihe | Ụkpụrụ nyocha | Nsonaazụ |
| Ọdịdị | kristal ọcha ma ọ bụ ntụ ntụ kristal;Mmasị acid siri ike | Dabara |
| njirimara | Infrared absorption Spectrum | Dabara |
| Ntụgharị a kapịrị ọnụ [α]20/D | +21.3° ruo +27.0° (C=5 na Phosphate Buffered Saline) | + 23.5 Celsius |
| Ọnọdụ Ngwọta (Nfefe) | Dị ọcha na enweghị agba ≥98.0% | 99.0% |
| Chloride (Cl) | ≤0.040% | <0.040% |
| Sulfate (SO4) | ≤0.030% | <0.030% |
| Ammonium (NH4) | ≤0.020% | <0.020% |
| Ígwè (Fe) | ≤20ppm | <20ppm |
| Ọla dị arọ (Pb) | ≤10ppm | <10ppm |
| Zinc (Zn) | ≤10ppm | <10ppm |
| Arsenic (As2O3) | ≤1.0pm | <1.0pm |
| Ihe ndị emetụtara | (Usoro HPLC) | |
| L-cystin | ≤0.50% | Dabara |
| L-cysteine | ≤0.50% | Dabara |
| N,N'-Diacetyl-L-Cystin | ≤0.50% | Dabara |
| N,S-Diacetyl-L-Cysteine | ≤0.50% | Dabara |
| Onye ọ bụla ọzọ adịghị ọcha | ≤0.50% | Dabara |
| Mgbakọta adịghị ọcha | ≤0.50% | Dabara |
| Ọnwụ na ihicha | ≤0.50% | 0.20% |
| Ihe fọdụrụ na mgbanye (Sulfated) | ≤0.20% | 0.05% |
| Nyocha | 98.5 ruo 101.0% (na akpọnwụ akpọnwụ) | 99.90% |
| Uru pH | 2.0 ruo 2.8 (1.0g na 100ml nke H2O) | 2.5 |
| Nsi biochemical | Na-agafe | Na-agafe |
| Ihe Organic Na-agbanwe agbanwe | Gafe | Gafe |
| Nchọpụta endonuclease | ≤0.1 EU/g | <0.1 EU/g |
| Mmechi | Ngwaahịa a sitere na nkwekọrịta nyocha na ọkọlọtọ AJI97 | |
| Isi ojiji | Amino acids;Ihe mgbakwunye nri;Ndị na-ahụ maka ọgwụ | |
ngwugwu: Fluorinated Bottle, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Chekwaa n'ime akpa mechiri emechi n'ụlọ nkwakọba ihe dị jụụ, kpọrọ nkụ na ikuku ikuku na-anọghị n'ihe na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) Usoro ule AJI97
N-Acetyl-L-Cysteine , mgbe akpọnwụwo, nwere ihe na-erughị 98.5 pasent na ọ bụghị karịa 101.0 pasent nke N-Acetyl-L-Cysteine (C5H9NO3S).
Nkọwa: kristal ọcha ma ọ bụ ntụ ntụ kristal, ụtọ acid siri ike.
Soluble soluble n'ime mmiri, soluble na ethanol, ihe fọrọ nke nta ka ọ bụrụ ihe a na-apụghị ịsacha na ether.
Solubility (H2O, g / 100g): 17 (20 ℃), 80 (40 ℃), 260 (60 ℃)
Nchọpụta: Tụlee ụdị nnabata infrared nke ihe nlele ahụ na nke ọkọlọtọ site na usoro diski bromide potassium.
Ntụgharị a kapịrị ọnụ [α] 20/D: nlele akpọnwụwo, C=8, ihe nchekwa phosphate
Ọnọdụ Ngwọta (Nfefe): 0.5g na 10ml nke H2O, spectrophotometer, 430nm, ọkpụrụkpụ sel 10mm.
Ọla dị arọ (Pb): 2.0g, (1), ntụgharị: 2.0ml nke Pb Std.(0.01mg/ml)
Zinc (Zn): Usoro nnabata atọm
Ihe ndị metụtara: Usoro HPLC
Ọnwụ na ihicha: Na oghere, na 70 ℃ maka awa 4
Ihe fọdụrụ na mgbanye (Sulfated): AJI Test 13
Nlele: Mịrị amị sample, 200mg, 0.05mol/L I2 1ml=16.320mg C5H9NO3S
pH: 1.0g na 100ml nke H2O
Oke nchekwa akwadoro na ọnọdụ: arịa ndị siri ike echekwara na okpomọkụ ụlọ a na-achịkwa (1 afọ).
N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) Uzo ule USP35
Nkọwa
Acetylcysteine nwere NLT 98.0% na NMT 102.0% nke L-threonine (C5H9NO3S), gbakọọ na ntọala akpọnwụwo.
Nchọpụta
A. AKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWỤKWASỊ"197K>
ASSAY
Usoro
Usoro mkpanaka: 6.8 g/L nke potassium phosphate monobasic.Gbanwee ya na phosphoric acid ka ọ bụrụ pH nke 3.0.
Sodium metabisulfite ngwọta: 0.5 mg/mL nke sodium metabisulfite n'ime mmiri, kwadebere ọhụrụ.
Ngwọta ọkọlọtọ dị n'ime: 5 mg/mL nke USP L-Phenylalanine RS na ngwọta sodium metabisulfite.
Ngwọta ngwaahịa ọkọlọtọ: 10 mg/mL nke USP acetylcysteine RS na ngwọta sodium metabisulfite.
Ngwọta ọkọlọtọ: 0.5 mg / ml nke USP acetylcysteine RS na 0.25 mg/mL nke USP L-Phenylalanine RS na Sodium metabisulfite ngwọta sitere na ngwọta ngwaahịa Standard na Internal standard solution.
Ihe ngwọta ngwaahịa: 10 mg / ml nke acetylcysteine na ngwọta sodium metabisulfite.
Ngwọta nlele: 0.5 mg/mL nke acetylcysteine na 0.25mg/mL nke USP L-Phenylalanine RS na ngwọta sodium metabisulfite sitere na ngwọta ngwaahịa ngwaahịa na ngwọta nke ime.
Sistemụ chromatographic
(Lee Chromatography <621>, Kwesịrị ekwesị Sistemu.)
Ụdị: LC
Ihe nchọpụta: UV 214 nm
Ogidi: 3.9-mm × 30-cm;mbukota L1
Ọnụego mmiri: 1.5 ml / min
Nha igba ogwu: 5µL
Sistemu kwesịrị ekwesị
[IHE-Oge njide ikwu maka acetylcysteine na L-phenylalanine bụ ihe dịka 0.5 na 1.0, n'otu n'otu.]
Kwesịrị ekwesị chọrọ
Mkpebi: NLT 6 n'etiti acetylcysteine na L-phenylalanine
Ngbanwe ọkọlọtọ emetụtara: NMT 2.0%
Nyocha
Ihe atụ: Ngwọta ọkọlọtọ na ngwọta nlele
Gbakọọ pasent nke acetylcysteine (C5H9NO3S) na akụkụ acetylcysteine a were:
Nsonaazụ = (RU/RS) × (CS/CU) × 100
RU = oke nzaghachi nke acetylcysteine na L-phenylalanine sitere na ngwọta Sample
RS = oke nzaghachi nke acetylcysteine na L-phenylalanine sitere na ngwọta ọkọlọtọ
CS = ntinye uche nke USP acetylcysteine RS na ngwọta ọkọlọtọ (mg/mL)
CU = ntinye nke acetylcysteine na ngwọta nlele (mg/mL)
Usoro nnabata: 98.0% -102.0% na ntọala akpọnwụwo
IHE adịghị ọcha
AKWỤKWỌ NA MKWA YA <281>: NMT 0.5%
Ọla dị arọ, Usoro II <231>
[Ịkpachara anya-Nlekọta ahụ maka mgbawa nwere ike ime.]
Nyocha: N'ụzọ dị nro, weta ihe nlele ahụ na 2 ml nke nitric acid, wee gaa n'ihu dịka akwadoro maka nkwadebe ule.
Usoro nnabata: NMT 10 ppm
Nnwale akọwapụtara
Ntụgharị anya, ntụgharị a kapịrị ọnụ <781S>
Ihe nchekwa: Gwakọta 29.5 ml nke 1 N sodium hydroxide, 50 ml nke 1 M monobasic potassium phosphate, na mmiri zuru oke iji mee 100 ml.Gbanwee na pH nke 7.0 ± 0.1 site na ịgbakwunye ihe ngwọta ọ bụla, dị ka ọ dị mkpa.
Ngwọta nlele: N'ime flask volumetric 25-mL, gwakọta 1.25 g na 1 mL nke edetate disodium solution (1 n'ime 100), tinye 7.5mL nke sodium hydroxide ngwọta (1 na 25), na mix ka igbari.Jiri ihe nchekwa mee ka ọ bụrụ olu.
Usoro nnabata: +21° ruo +27°
pH <791>: 2.0-2.8 na ngwọta (1 n'ime 100)
Ọnwụ na nkụ <731>: Kpochapụ ihe nlele na nrụgide nke ihe dịka 50 mm nke mer cury na 70 Celsius maka awa 4: ọ na-efunahụ NMT 1.0% nke ibu ya.
NKWUO GBASARA YA
Nkwakọ ngwaahịa na nchekwa: Chekwaa n'ime akpa siri ike, ma chekwaa na okpomọkụ nke ụlọ a na-achịkwa.
Ụkpụrụ ntụaka USP <11>
USP acetylcysteine RS
USP L-Phenylalanine RS
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Ọrụ & Ngwa nke N-Acetyl-L-Cysteine (Ac-Cys-OH; NAC) (CAS: 616-91-1) ntụ ntụ
1. N-Acetyl-L-Cysteine , nke a makwaara dị ka N-Acetylcysteine ma ọ bụ Acetylcysteine (NAC), bụ ọgwụ na-emepụta ọgwụ na ihe oriri na-edozi ahụ nke a na-ejikarị eme ihe dị ka onye na-ahụ maka mucolytic na nchịkwa nke paracetamol (acetaminophen) na-emebiga ihe ókè.Ojiji ndị ọzọ gụnyere njupụta sulfate na ọnọdụ, dị ka Autism, ebe cysteine na sọlfọ amino acid nwere ike ibelata.
2. N-Acetyl-L-Cysteine bụ ihe mmepụta nke cysteine ebe otu acetyl jikọtara na nitrogen atom.A na-ere onyinye a dị ka mgbakwunye nri nri na-ekwukarị na mmetụta antioxidant na imeju na-echebe.A na-eji ya dị ka ọgwụ ụkwara n'ihi na ọ na-agbaji njikọ disulfide na imi ma na-amịnye ya, na-eme ka ọ dịkwuo mfe ụkwara.Ọ bụkwa omume a nke imebi agbụ disulfide na-eme ka ọ baa uru n'ịbelata imi na-adịghị ahụkebe na ndị ọrịa cystic na pulmonary fibrosis.
3. Acetylcysteine bụ onye na-ahụ maka mucolytic nwere mmetụta mucolytic siri ike.Otu sulfhydryl dị na molekul nwere ike imebi njikọ disulfide na glycoprotein polypeptide yinye na sputum, si otú ahụ belata viscosity nke sputum, na-eme ka sputum mmiri mmiri na mfe ụkwara.Ngwaahịa a nwekwara ike imebi eriri DNA na sputum purulent, yabụ na ọ bụghị naanị igbari sputum na-acha ọcha, kamakwa sputum purulent.Maka ndị ọrịa nke ndị na-atụ anya izugbe na-adịghị arụ ọrụ, ngwaahịa a ka nwere ike ịdị irè.
4. A na-eji ya dị ka ọgwụ agbaze phlegm.A na-eji ya na nyocha biochemical na ọgwụ dịka ọgwụ mgbochi maka nsị phlegm na acetaminophen.Biochemical reagent, ọgwụ, ngwaahịa a na-eji dị ka expectorant, kwuru na phlegm dị mfe ihicha.
5. Mmetụta ndị a na-ahụkarị gụnyere ọgbụgbọ na ọgbụgbọ mgbe ejiri ọnụ ewere ya. Akpụkpọ ahụ nwere ike na-acha ọbara ọbara mgbe ụfọdụ ma na-egbuke egbuke n'ụdị ọ bụla.Ụdị anaphylaxis na-abụghị nke mgbochi nwekwara ike ime.Ọ na-egosi na ọ dị mma n'afọ ime.Maka oke paracetamol, ọ na-arụ ọrụ site n'ịbawanye ọkwa nke glutathione, antioxidant nke nwere ike iwepụ ngwaahịa mmebi nsi nke paracetamol.Mgbe ikuru ume, ọ na-eme dị ka mucolytic site na ibelata oke imi.
6. Emebere acetylcysteine na mbụ na 1960 wee bata n'ọrụ ahụike na 1968. Ọ dị na Ndepụta ọgwụ ndị dị mkpa nke World Health Organisation, nke depụtara ọgwụ kachasị dị nchebe na nke kachasị dị mkpa na usoro ahụike.A na-enweta ya dị ka ọgwụ n'ozuzu ma ọ dịghị ọnụ.
7. N-Acetyl-L-Cysteine bụ acetylated ụdị L-cysteine nke a na-etinye n'ọrụ nke ọma ma jiri ya mee ihe.Ọ bụkwa antioxidant nke na-enyere aka megide nje.A na-eji N-Acetyl-l-Cysteine dị ka ihe nchebe imeju na ịgbaji pulmonary na bronchial imi.
8. N-Acetyl-L-Cysteine nwere ike ịkwalite ọkwa glutathione na sel.
9. N-Acetyl-L-Cysteine bụ amino acid dị mkpa nke nwere ọnọdụ, otu n'ime amino acid atọ nwere sọlfọ, ndị ọzọ bụ taurine (nke enwere ike imepụta site na L-cysteine ) na L-methionine nke L-cysteine nwere ike. a ga-emepụta n'ime ahụ site na usoro ọtụtụ nzọụkwụ.
10. N-Acetyl-L-Cysteine nwere ike ime dị ka antioxidant, nwere ike igbochi ọrịa imeju, ma nwee ike inye aka na-eme ka onye dayameta nke ntutu dị ugbu a gbasaa ma ọ bụrụ na a na-ewere ya mgbe niile.
11. Ngwa na ngalaba ahụike dị ka onye na-ahụ maka usoro iku ume, enwere ike iji ya dị ka ọgwụ maka igbari phlegm drum.ọ nwere ike ịgwọ bronchitis.Ọzọkwa, N-Acetyl-L-Cysteine nwere ike iji dị ka ọgwụ mgbochi mgbe nsị acetaminophen.
12. Ngwa na ịchọ mma ubi N-Acetyl-L-Cysteine nwere mmetụta dị ukwuu na ikpochapụ oxygen free radicals na ndị ọzọ oxides na slowing usoro ịka nká, ọ nwekwara ike ịkpaghasị melanin mmepụta, na-enye aka iji kpochapụ freckle na akpụkpọ ahụ.
13. Enwere ike iji ngwa na nri anụmanụ N-Acetyl-L-Cysteine dị ka ihe mgbakwunye nri.
14. Ihe ịchọ mma a na-ejikarị eme mmiri mma, mmiri mmiri perm, ude nlekọta anụ ahụ na-egbochi anwụ.Nwere ọrụ iji gbochie ịka nká.N-Acetyl-l-Cysteine nwere ike igbochi ma gwọọ mmerụ ahụ radieshon.N-acetyl Cysteine nwere ike wepu melanin akpụkpọ ahụ n'onwe ya, gbanwee ọdịdị akpụkpọ ahụ n'onwe ya, akpụkpọ ahụ na-aghọ ọcha eke.
15. Ihe mgbakwunye nri.A na-eji achịcha eme ihe, iji kwalite nhazi nke gluten ma kwalite gbaa ụka, ebu, gbochie ịka nká.A na-eji ihe ọ juiceụ eke eke eme ihe iji gbochie vitamin C site na oxidizing na igbochi ihe ọṅụṅụ na-acha aja aja.
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