N-Hydroxysuccinimide (HOSu) CAS 6066-82-6 Njikọta Reagent Dị Ọcha> 99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6) nwere àgwà dị elu.Ruifu Chemical na-enye usoro nchekwa reagents na reagents njikọ.Ruifu nwere ike ịnye nnyefe zuru ụwa ọnụ, ọnụahịa asọmpi, obere na nnukwu ọnụọgụ dị.Ịzụta N-Hydroxysuccinimide,Please contact: alvin@ruifuchem.com
Aha Chemical | N-Hydroxysuccinimide |
Ụdị okwu | HOSU;NHS;1-Hydroxysuccinimide;1-Hydroxy-2,5-Pyrrolidinedione;N-Hydroxy-2,5-dioxopyrrolidine |
Ọnọdụ Ahịa | Na ngwaahịa, Mass Production |
Nọmba CAS | 6066-82-6 |
Usoro ihe omimi | C4H5NO3 |
Ibu molekụla | 115.09 g/mol |
Ebe Na-agbaze | 93.0 ~ 98.0 ℃ (ọkụ) |
Njupụta | 1.649 |
Mmetụta | Hygroscopic.Okpomọkụ na-enwe mmetụta, mmetụta nke mmiri |
Solubility na Dioxane | Soluble na Dioxane, Ihe fọrọ nke nta ka ọ bụrụ nghọta |
Solubility na Mmiri | Soluble na Mmiri |
Okpomọkụ nchekwa. | Ebe dị jụụ na nkụ (2 ~ 8 ℃) |
COA & MSDS | Dị |
Otu | Njikọ njikọ Reagents |
Ụdị | Ruifu Chemical |
Ihe | Ụkpụrụ nyocha | Nsonaazụ |
Ọdịdị | White Crystalline ntụ ntụ | Na-akwado |
Ebe Na-agbaze | 93.0 ~ 98.0 ℃ | 94.0 ~ 97.0 ℃ |
Ọnwụ na ihicha | <0.50% | 0.15% |
Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) | 99.5% |
Spectrum infrared | Dabara na Ọdịdị | Na-akwado |
Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị | Na-akwado |
Mmechi | A nwalela ngwaahịa a wee kwado nkọwapụta |
Usoro mkpanaka: 0.1% ngwọta phosphoric acid: acetonitrile = 90:10
Ogologo ogologo: 220nm
Onu ogugu: 1ml/min
ngwugwu:Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Mmiri nwere mmetụta.Chekwaa n'ime akpa mkpuchi mkpuchi n'ụlọ nkwakọba ihe dị jụụ na nkụ (2 ~ 8 ℃) pụọ na ihe ndị na-ekwekọghị ekwekọ.Chebe site na ìhè na mmiri mmiri.
Mbupu:Nyefee n'ụwa niile site na FedEx / DHL Express.Nye nnyefe ngwa ngwa na ntụkwasị obi.
Kedu ka esi azụta?Biko kpọtụrụDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Ahụmịhe afọ 15?Anyị nwere ihe karịrị 15 afọ nke ahụmahụ na mmepụta na mbupụ nke a dịgasị iche iche nke elu mma pharmaceutical intermediates ma ọ bụ ezi kemịkal.
Isi ahịa?Na-ere ahịa ụlọ, North America, Europe, India, Korea, Japanese, Australia, wdg.
Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.
Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
Oge Mbuga ozi? Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ.
Ụgbọ njem?Site Express (FedEx, DHL), nke ikuku, site n'oké osimiri.
Akwụkwọ?Mgbe ọrụ ahịa gasịrị: COA, MOA, ROS, MSDS, wdg nwere ike ịnye.
Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
Usoro ịkwụ ụgwọ?A ga-ebu ụzọ ziga akwụkwọ ọnụahịa Proforma mgbe nkwenye nke iwu, kpuchiri ozi ụlọ akụ anyị.Ịkwụ ụgwọ site na T/T (Telex Nyefee), PayPal, Western Union, wdg.
Ihe akara egwu Xi - iwe
Koodu ihe egwu
36/37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ.
Nkọwapụta nchekwa
S22 - Ekula uzuzu.
S24/25 - Zere kọntaktị na akpụkpọ ahụ na anya.
S26 - N'ihe banyere kọntaktị na anya, kpochaa ozugbo na ọtụtụ mmiri ma chọọ ndụmọdụ ahụike.
S36 - Yiri uwe nchebe kwesịrị ekwesị.
WGK Germany 3
TSCA Ee
Koodu mpaghara:: 2925190090
Ihe ndetu Hazard na-ewe iwe
N-Hydroxysuccinimide (HOSu) (CAS: 6066-82-6), reagent maka nkwadebe nke esters na-arụ ọrụ nke amino acid.Peptide siri ike usoro njikọ njikọ.
A na-ejikarị N-Hydroxysuccinimide na-enyere aka ijikọta peptide mediated carbodiimide site n'ịmepụta ester intermediate na-arụ ọrụ site na condensation nke elu carboxyl otu na NHS.NHS-reactive ester intermediate nwere ike ibute ọgụ nucleophilic site na amines ndị bụ isi ma na-ebute nguzobe nke njikọ amide kwụsiri ike n'etiti elu biomaterial na N-terminus nke peptide.
N-Hydroxysuccinimide bụ succinimide hydroxylated nke a na-ejikarị eme ihe na ntinye nke acid carboxylic na NHS-esters iji kwalite njikọ na nucleophiles.A na-ejikarị usoro a eme ihe n'ịkwalite ụdị fluorophores acid n'efu maka ịkwalite njikọ nke fluorophores ndị a na amine residues nke protein.A kọwakwara ojiji nke NHS ester activation na njikọ nke N-acyl amino acids.
A na-eji maka njikọ nke amino acid nchebe, semi-synthetic kanamycin na ọgwụ intermediates.N-hydroxybutyldiimide na usoro ya bụ ihe dị mkpa akụrụngwa maka njikọ nke peptides, ọgwụ nje, amino acids na protein.N-hydroxybutyldiimide na-eji na nkwadebe nke nọ n'ọrụ. esters, na mgbochi nke mmetụta anya na-arụ ọrụ nke peptide njikọ nwere ọtụtụ USES na nkà mmụta ọgwụ, ma bụrụkwa ihe bụ isi kemịkalụ.
A na-eji N-Hydroxysuccinimide mee ihe maka mmụba dị mma na usoro carbodiimide.A na-ejikwa ya rụọ ọrụ otu carboxyl ma meghachi omume na amine iji mepụta amide.Ọ na-etinye aka na nkwadebe nke N-hydroxymaleimide-styrene copolymer.
A kwadebere N-Hydroxysuccinimide dị ka ndị a: 100g (1.0mol) succinic anhydride na 70g (1.0mol) nke hydroxylamine hydrochloride na-ekpo ọkụ ọnụ, a na-echekwa usoro mmeghachi omume n'okpuru nrụgide na-adịghị mma iji wepụ ihe ndị na-emepụta ihe na-emepụta, ma na-ekpo ọkụ ngwa ngwa n'elu 125 ℃. , wee jiri nwayọọ nwayọọ na-ebili na 160 ℃ mgbe 1H gasịrị.A kwụsịrị ikpo ọkụ na mgbe okpomọkụ dara na 125 ℃, a na-awụsa mmeghachi omume mmiri n'ime diethyl ether ma kpalie ike.Mgbe a gwọchara ngwaahịa ahụ, a na-ewepụ oyi akwa ether, a na-ekpocha ngwaahịa a gwọrọ ka ọ sie ya na 400ml nke butanol, a na-ekpo ọkụ na-ekpo ọkụ, na filtrate na-adị jụụ ngwa ngwa ruo 0 ℃.Mgbe nzacha 1H gasịrị, a na-eji butanol na diethyl ether sachaa kristal ndị ahụ, na ngwaahịa crude enwetara na-emegharịghachi site na ethyl acetate iji nweta 50g nke ngwaahịa emechara na 44% mkpụrụ.
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