Naproxen CAS 22204-53-1 Ịdị ọcha> 99.5% (HPLC)

Naproxen (CAS: 22204-53-1) bụ ọgwụ na-adịghị na steroidal anti-inflammatory, ọ bụ PG synthase inhibitor, nke nwere ike igbochi prostaglandin synthetase, ọ nwere mmetụta analgesic na antipyretic dị ịrịba ama, absorption ọnụ na-adị ngwa ngwa na zuru oke, 2 ruo Mgbe awa 4 gachara, ntinye plasma na-erute elu, n'ime ọbara, ihe karịrị 99% na-ejikọta ya na protein plasma, t1/2 bụ awa 13 ruo 14, ihe dịka 95% na-apụ na mmamịrị site na prototype na metabolites.A na-eji ya na ụlọ ọgwụ maka ọgwụgwọ ọrịa ogbu na nkwonkwo na rheumatoid ogbu na nkwonkwo, osteoarthritis, ankylosing spondylitis, gout, ogbu na nkwonkwo, tenosynovitis.nwekwara ike iji mee ihe na-ebelata ihe mgbu nke musculoskeletal sprains, contusions,mmebi na dysmenorrhea.Ma ekwesiri iburu n'uche na dị ka ọgwụ ndị ọzọ na-abụghị steroidal anti-inflammatory, otu mmeghachi omume ọjọọ nke eriri afọ nwere ike ime n'oge ọ bụla mgbe ị na-ewere naproxen n'oge ọgwụgwọ, ya mere a na-akwụgide ndị ọrịa gastroduodenal ọnyá afọ na-arụ ọrụ, ndị ọzọ na-arịa ọrịa eriri afọ ga-ewere nke a. ọgwụ n'okpuru nlekọta ahụike chiri anya.A na-emepụta Naproxen site na 2-methoxynaphthalene na (+) -isomer nwetara site na mkpebi ya na cinchonidine (61).Ewebatara ya na United States n'afọ 1976 na, dị ka ọgwụ ọ bụla, so na NSAID ndị a ma ama.A na-ere ya dị ka S- (+) -enantiomer, ma ọ na-adọrọ mmasị, nnu sodium nke (-) isomer dịkwa n'ahịa dị ka Anaprox.Dị ka onye na-egbochi prostaglandin biosynthesis, ọ na-enwe ike 12 ugboro karịa aspirin, 10 ugboro karịa phenylbutazone, ugboro atọ na anọ karịa ibuprofen, na ugboro anọ karịa fenoprofen, ma ọ bụ ihe dịka 300 ugboro obere ike karịa. Indomethacin.