Olmesartan Medoxomil CAS 144689-63-4 Ịdị Ọcha>99.5% (HPLC) API Foto egosipụtara

Olmesartan Medoxomil CAS 144689-63-4 Ịdị ọcha>99.5% (HPLC) Ụlọ ọrụ API

Nkọwa dị mkpirikpi:

Aha Chemical: Olmesartan Medoxomil

Nọmba: 144689-63-4

Dị ọcha:> 99.5% (HPLC)

Ọdịdị: Ọcha ruo Ọcha Cyrstalline ntụ ntụ

Angiotensin II nnabata antagonist.Mgbochi hypertensive

E-Mail: alvin@ruifuchem.com

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Ruifu Chemical Supply Olmesartan Medoxomil Intermediates nwere oke mma:
4,5-Dimethyl-1,3-Dioxol-2-Otu (DMDO) CAS 37830-90-3
4-Chloromethyl-5-Methyl-1,3-Dioxol-2-One (DMDO-Cl) CAS 80841-78-7
Ethyl 4- (1-Hydroxy-1-Methylethyl) -2-Propyl-Imidazole-5-Carboxylate CAS 144689-93-0
Diethyl 2-Propyl-1H-Imidazole-4,5-Dicarboxylate CAS 144689-94-1
Triyl Olmesartan Ethyl Ester CAS 144690-33-5
Triyl Olmesartan Acid CAS 761404-85-7
N2-Tryl Olmesartan Acid CAS 752179-89-8
Triyl Olmesartan Medoxomil CAS 144690-92-6
Olmesartan Medoxomil CAS 144689-63-4

Njirimara kemịkalụ:

Aha Chemical	Olmesartan Medoxomil
Ụdị okwu	4- (1-Hydroxy-1-methylethyl) -2-propyl-1-[2'- (2H-tetazol-5-yl) [1,1'-biphenyl] -4-yl] methyl] -1H- imidazole-5-carboxylic acid (5-Methyl-2-oxo-1,3-dioxol-4-yl) methyl Ester;CS-866
Nọmba CAS	144689-63-4
Nọmba CAT	RF-PI1730
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C29H30N6O6
Ibu molekụla	558.60
Ebe Na-agbaze	180 ℃ (Dec.)
Mmiri Solubility	Na-adịghị edozi na Mmiri;Soluble dị ntakịrị na DMSO
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ọcha ruo Ọcha Cyrstalline ntụ ntụ
njirimara	IR, HPLC, UV: Ga-emerịrị n'ụkpụrụ ntụaka
Ụzọ ịdị ọcha / nyocha	> 99.5% (HPLC na Anhydrous na ihe mgbaze na-enweghị ihe mgbaze)
Ọnwụ na ihicha	<0.50%
Ihe fọdụrụ na mgbanye	<0.10%
Ihe ndị emetụtara
Olmesartan RRT 0.2	<0.50%
Ngwakọta metụtara Olmesartan Medoxoil A. RRT 0.7	<0.20%
Olefinic adịghị ọcha RRT 1.6	<0.50%
N-Alkyl adịghị ọcha RRT 3.4	<0.10%
Ọdịghị ọcha ọ bụla ọzọ	<0.10%
Mgbakọta adịghị ọcha	<0.50%
Ọla dị arọ (dị ka Pb)	<10ppm
pH nke Ngwọta (2%, W/V)	4.5 ruo 6.5
Nlele ọkọlọtọ	Ụkpụrụ ụlọ ọrụ;USP Standard
Ojiji	API

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

Ajụjụ:

Ngwa:

Olmesartan Medoxomil (CS-866) (CAS: 144689-63-4) bụ ike na nhọrọ angiotensin II ụdị 1 (AT (1)) antagonist na-anabata ya na IC50 nke 66.2 μM., eji na ọgwụgwọ ọbara mgbali elu.Ejiri ya dị ka ihe mgbochi ọbara mgbali elu.Olmesartan na-arụ ọrụ site na igbochi njikọ nke angiotensin II na ndị na-anabata AT1 na akwara vaskụla.Site na igbochi njide kama njikọ nke angiotensin II, Olmesartan na-egbochi nzaghachi nchịkwa na-adịghị mma na nzuzo nke renin.Olmesartan Medoxomil bụ ọgwụ pro-ọgwụ nke ewepụrụ na metabolite nọ n'ọrụ, olmesartan.Emebere Olmesartan Medoxomil na US ka Benicar, ọgwụgwọ ọnụ maka ọbara mgbali elu.