Olopatadine Hydrochloride Intermediate CAS 27710-82-3 Ịdị Ọcha>99.0% (HPLC)

Nkọwa dị mkpirikpi:

[3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide

Nọmba: 27710-82-3

Dị ọcha:> 99.0% (HPLC)

Ọdịdị: White ka Gbanyụọ-White Crystal Powder

Ọkara nke Olopatadine Hydrochloride (CAS 140462-76-6)

Ogo dị elu, mmepụta azụmahịa

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Onye na-ebute ụzọ nke Olopatadine Hydrochloride Intermediates
Olopatadine Hydrochloride CAS 140462-76-6
Isoxepac CAS 55453-87-7
[3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide CAS 27710-82-3
Please Contact: alvin@ruifuchem.com

Njirimara kemịkalụ:

Aha Chemical [3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide
Ụdị okwu (3-Dimethylaminopropyl) triphenylphosphonium Bromide HBr
Nọmba CAS 27710-82-3
Nọmba CAT RF2698
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C23H28Br2NP
Ibu molekụla 509.27
Ebe Na-agbaze 283.0 ~ 285.0 ℃
Nkwụsi ike Hygroscopic
Solubility Chloroform (obere), methanol (obere)
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ntụ ntụ kristal na-acha ọcha ruo na-acha ọcha
Ụzọ ịdị ọcha / nyocha > 99.0% (HPLC)
Usoro nyocha / nyocha > 99.0% (Titration)
Ọnwụ na ihicha <0.50%
Otu adịghị ọcha <0.50%
Mgbakọta adịghị ọcha <1.00%
1 H NMR Spectrum Nkwekọrịta na Ọdịdị
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji Ọkara nke Olopatadine Hydrochloride (CAS: 140462-76-6)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

Ike zuru oke: akụrụngwa na ndị ọrụ nka zuru oke

Ọrụ Ọkachamara: Otu nkwụsị ịzụrụ ọrụ

Ihe ngwugwu OEM: ngwugwu omenala na akara dị

Nnyefe ngwa ngwa: Ọ bụrụ n'ime ngwaahịa, ekwenyere nnyefe ụbọchị atọ

Nkwanye kwụsiri ike: Jikwaa ngwaahịa ezi uche dị na ya

Nkwado nka na ụzụ: Ngwọta teknụzụ dị

Ọrụ Synthesis Custom: sitere na gram ruo kilos

Ogo dị elu: guzobe usoro mmesi obi ike zuru oke

Ajụjụ:

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OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.

Ihe atụ?Ọtụtụ ngwaahịa na-enye ihe nlele efu maka nyocha dị mma, ndị ahịa kwesịrị ịkwụ ụgwọ mbupu.

Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.

MOQ?Enweghị MOQ.A na-anabata obere usoro.

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Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.

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Ngwa:

[3- (Dimethylamino) propyl] triphenylphosphonium Bromide Hydrobromide (CAS: 27710-82-3) bụ etiti nke Olopatadine Hydrochloride (CAS: 140462-76-6).Olopatadine Hydrochloride bụ ọgwụ na-egbochi ihe nfụkasị ahụ.Ọ nwere mmetụta abụọ nke igbochi ntọhapụ nke histamine na nhọrọ na-emegide ndị na-anabata HI, na enweghị mgbochi nke sistemu ụjọ etiti yana mmetụta ndị na-egbu egbu nke obi na-ejikarị ọgwụ ndị na-anabata HI antagonist antiallergic.Olopatadine Hydrochloride nwere ike ọ bụghị naanị igbochi ntọhapụ nke histamine site na mkpụrụ ndụ mast, kamakwa na-emegide ndị na-anabata H1 nke ọma, ọ nweghịkwa mmetụta na ndị na-anabata α adrenergic, ndị na-anabata dopamine, na M1 na M2 ndị na-anabata ya.N'ime ha, mmetụta dị n'akụkụ nke usoro nhụjuanya nke etiti dị ole na ole, bụ ọgbọ ọhụrụ nke ọgwụ antiallergic nke nhọrọ.Olopatadine bụ onye nwere ike, onye na-emegide onye na-anabata H1 histamine (Ki = 16-41.1 nM), nwere njikọ dị ala maka ndị na-anabata H2 na H3 (Ki = 43.4 na 172 μM, n'otu n'otu).Ọ na-egbochi mgbanwe phosphoinotide na-akpata histamine na sel dịpụrụ adịpụ (IC50 = 9.5-39.9 nM) ma gbochie anaphylaxis akpụkpọ anụ na oke (ED50 = 49 μg / kg) na bronchoconstriction anaphylactic na pigs Guinea (ID50 = 30 ).Olopatadine dị irè n'ịgwọ rhinitis nfụkasị na conjunctivitis.Ọ na-egbochikwa itching na ndị ọrịa nwere urticaria na-adịghị ala ala ejiri nke ọma na-achịkwa.N'ime ụmụ mmadụ, antihistamine a anaghị akpata mmerụ ahụ ma ọ bụ psychomotor na usoro ọgwụgwọ.

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