Omeprazole Sulfide CAS 73590-85-9 Dị Ọcha> Ụlọ ọrụ 99.0% (HPLC)
Ruifu Chemical Supply Omeprazole Intermediates With High Purity
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Omeprazole Sulfide CAS 73590-85-9
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2,3,5-Trimethylpyridine CAS 695-98-7
Aha Chemical | Omeprazole Sulfide |
Ụdị okwu | Ufiprazole;Omeprazole sọlfọ ether;Esomeprazole EP adịghị ọcha C;Omeprazole EP adịghị ọcha C;5-Methoxy-2-[[(4-Methoxy-3,5-Dimethyl-2-Pyridyl)methyl] thio] benzimidazole;5-Methoxy-2-{[(4-Methoxy-3,5-Dimethyl-2-Pyridinyl)methyl]thio}-1H-Benzimidazole |
Nọmba CAS | 73590-85-9 |
Nọmba CAT | RF-PI1914 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C17H19N3O2S |
Ibu molekụla | 329.42 |
Ebe Na-agbaze | 122.0 ruo 126.0 ℃ |
Solubility | Soluble na methanol |
Njupụta | 1.28±0.10 g/cm3 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ ma ọ bụ kristal |
Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) |
Ọnwụ na ihicha | <1.00% |
Ihe fọdụrụ na mgbanye | <0.20% |
Ọla dị arọ (dị ka Pb) | <20ppm |
Otu adịghị ọcha | <0.50% |
Mgbakọta adịghị ọcha | <1.00% |
Spectrum infrared | Dabara na Ọdịdị |
Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Omeprazole / Esomeprazole dị n'etiti |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Omeprazole Sulfide (CAS: 73590-85-9) bụ ihe etiti ejiri na mmepụta nke proton pump inhibitors gastric, Omeprazole (CAS: 73590-58-6) na Esomeprazole (CAS: 119141-88-7), Esomeprazole Sodium ( OZI: 161796-78-7).Dị ka ngwaahịa na-emebi emebi, a na-akọ na ọ bụ onye na-egbochi cytochrome P450 2C19 na microsomes imeju mmadụ (IC50 = 9.7 μM).Omeprazole sulfide bụ metabolite nke Omeprazole.Esomeprazole Sodium bụ ụdị nnu sodium nke esomeprazole.Ọ bụ ọgwụ mgbochi ọnya a na-ejikarị eme ihe, nke ụlọ ọrụ Sweden Astra Zeneca buru ụzọ mepụta nke ọma.Ọ bụ nke proton pump inhibitor.Ihe mgbochi mgbapụta proton bụ nhọrọ izizi maka ọgwụgwọ ọnya peptic, ọrịa gastro-esophageal reflux na ọrịa ndị ọzọ metụtara acid.Ugbu a a na-ejikarị PPI eme ihe gụnyere ụdị ise: Omeprazole, Lansoprazole, Rabeprazole, Pantoprazole na Esomeprazole.Dị ka PPI mbụ, a matala ịdị irè ọgwụ omeprazole n'ịgwọ ọrịa ndị metụtara acid.Esomeprazole bụ S-isomer nke Omeprazole, nke nwere ike ibelata secretion acid gastric site na usoro ezubere iche.Ọ bụ ihe mgbochi kpọmkwem maka proton pump inhibitor na cell parietal.N'ihi uru metabolic nke esomeprazole, ọ nwere bioavailability dị elu yana pharmacokinetics na-agbanwe agbanwe karịa onye otu ya, Omeprazole Sodium, na-abawanye ọgwụ na-erute mgbapụta proton.Ọrụ ya nke njikwa acid gastric dị mma karịa ndị na-egbochi nfuli proton ndị ọzọ dị ka Lansoprazole, Pantoprazole, na Rabeprazole.