Palbociclib CAS 571190-30-2 Ịdị Ọcha>99.5% (HPLC) API Foto egosipụtara

Palbociclib CAS 571190-30-2 Ịdị Ọcha> 99.5% (HPLC) Ụlọ ọrụ API

Nkọwa dị mkpirikpi:

Aha Chemical: Palbociclib

CAS: 571190-30-2

Dị ọcha:> 99.5% (HPLC)

Ọdịdị: White ma ọ bụ Gbanyụọ-Ọcha ntụ ntụ

API Na Ọgwụgwọ Ọrịa Cancer

Ogo dị elu, mmepụta azụmahịa

E-Mail: alvin@ruifuchem.com

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Ruifu Chemical Supply Palbociclib metụtara Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H) -otu CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-otu CAS 1013916-37-4

Njirimara kemịkalụ:

Aha Chemical	Palbociclib
Ụdị okwu	PD-0332991;Otava-Bb 1115529;Ibrance
Nọmba CAS	571190-30-2
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C24H29N7O2
Ibu molekụla	447.54
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ọcha ma ọ bụ Gbanyụọ-Ọcha ntụ ntụ
1H NMR Spectrum	Nkwekọrịta na Ọdịdị
HPLC	Nkwekọrịta na Ọdịdị
Ihe ndị emetụtara
Ọdịghị ọcha nke Onwe Onye	<0.50%
Mgbakọta adịghị ọcha	<1.00%
Ọnwụ na ihicha	<0.50%
Ihe fọdụrụ na mgbanye	<0.10%
Ọla dị arọ	<10ppm
Ụzọ ịdị ọcha / nyocha	> 99.5% (HPLC)
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	API, Na Ọgwụgwọ Ọrịa Cancer

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

Ajụjụ:

Ngwa:

Palbociclib (CAS: 571190-30-2) bụ onye na-egbochi cyclin-dependent kinase (CDK) nke nwere ike ịrụ ọrụ antineoplastic.Palbociclib na-ahọrọ nke ọma na-egbochi cyclin-based kinase 4 (CDK4) na 6 (CDK6), si otú a na-egbochi retinoblastoma (Rb) protein phosphorylation n'isi mmalite nke G1 na-eduga na njide okirikiri cell.Nke a na-egbochi mmeghari DNA ma na-ebelata mmụba cell tumor.Palbociclib bụ onye nnọchi anya mbụ nke klas ọgwụ ọhụrụ nke inhibitors kinase inhibitors cyclin.Mmetụta a na-egbochi mmụba cell (mkpụrụ ndụ na nkewa).A na-eji ya dị ka onye na-ahụ maka antineoplastic na ọrịa cancer ara dị elu ma ọ bụ metastatic.