Pantoprazole Sodium CAS 138786-67-1 Ịdị Ọcha ≥99.0% (HPLC) Ụlọ ọrụ API
Aha Chemical | Pantoprazole sodium |
Ụdị okwu | 5- (Difluoromethoxy) -2- (((3,4-Ddimethoxy-2-Pyridinyl)methyl) sulfinyl) -1h-Benzimidazole Sodium |
Nọmba CAS | 138786-67-1 |
Nọmba CAT | RF-API107 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C16H14F2N3NaO4S |
Ibu molekụla | 405.35 |
Ebe Na-agbaze | 199.0 ruo 202.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ |
Solubility | Soluble efu na methanol, ethanol na mmiri |
Nyochaa maka sodium | Ịdị Mma |
IR Spectrum | Na-akwado Spectrum Reference |
pH | 9.0-11.5 |
Ọdịnaya Ọdịnaya (KF) | 4.5-8.0% |
Ihe ndị emetụtara | Usoro HPLC |
Nnukwu adịghị ọcha | ≤0.50% |
Mgbakọta adịghị ọcha | ≤1.0% |
Ọla dị arọ | ≤20ppm |
Ihe mgbaze fọdụrụnụ | Zute nkọwapụta ahụ |
Nyocha (nke HPLC) | ≥99.0% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | API;Onye na-egbochi mgbapụta Proton (PPI) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Pantoprazole Sodium (CAS: 138786-67-1) bụ onye na-arụ ọrụ ọnụ na proton pump inhibitor (PPI) nke na-egbochi usoro ikpeazụ na mmepụta gastric acid site na ijikọ ya na (H +, K+) -ATPase enzyme usoro na nzuzo nke elu. cell parietal gastric.Pantoprazole sodium, benzimidazole dochie anya, bụ ihe mgbochi H+/K+-ATPase nwere ike nwere IC50 nke 6.8 μM.Pantoprazole sodium na-eme ka nkwụsi ike pH dịkwuo mma ma nwee mgbochi nzuzo, ọrụ mgbochi ọnya.A na-eji Pantoprazole na-agwọ ọrịa: Ọgwụgwọ nke Esophagitis nke Erosive Esophagitis na-adị mkpụmkpụ nke jikọtara ya na Gastroesophageal Reflux Disease (GERD) Nlekọta nke ọgwụgwọ nke Erosive Esophagitis Pathological Hypersecretory Conditions gụnyere Zollinger-Ellison (ZE) Syndrome.