Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1 Assay 97.5 ~ 102.0% Ụlọ ọrụ
Ruifu Chemical Supply With High Purity
Paroxetine Hydrochloride Hemihydrate CAS 110429-35-1
N-Methyl Paroxetine CAS 110429-36-2
| Aha Chemical | Paroxetine Hydrochloride Hemihydrate |
| Ụdị okwu | (3S, 4R) - - - 3 - [(1,3-Benzodioxol-5-yloxy) methyl] -4- (4-fluorophenyl) piperidine Hydrochloride Hemihydrate;Paxil;Serokat;BRL29060 Hydrochloride Hemihydrate;BRL29060A Hemihydrate;Paroxetine-D4 HCl |
| Nọmba CAS | 110429-35-1 |
| Nọmba CAT | RF-PI1946 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C19H20FNO3·HCl·1/2H2O |
| Ibu molekụla | 374.84 |
| Ebe Na-agbaze | 140.0 ~ 143.0 ℃ |
| Ntụgharị a kapịrị ọnụ [α]20/D | -88.0° ruo -92.0° (C=1, MeOH, Calcd.on anh.substance) |
| Solubility | Ihe Na-adịghị Mma Na Mmiri;Soluble na Dimethylformamide, methanol;Soluble na ethanol |
| Ụdị | Ruifu Chemical |
| ọdịnaya | Nkọwapụta | Nsonaazụ |
| Ọdịdị | White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ | Kwado |
| njirimara A | Ụdị nnabata infrared kwesịrị ịdị na-adaba na nrụtụ aka | Kwado |
| njirimara B | Ebe kachasị elu na oge njide nke ngwọta ule kwesịrị ikwekọ na ngwọta ntụaka | Kwado |
| njirimara C | Mmiri (nke KF) | Kwado |
| njirimara D | Mmeghachi omume nke chlorides | Kwado |
| adịghị ọcha D | ≤0.20% | Adịghị |
| adịghị ọcha G | ≤0.001% | |
| Ihe ndị emetụtara | adịghị ọcha A: ≤0.30% | 0.03% |
| Ihe adịghị ọcha na-akọwapụtaghị: Maka adịghị ọcha ọ bụla, ≤0.10% | 0.06% | |
| Mkpokọta adịghị ọcha: ≤0.50% | 0.10% | |
| Ọla dị arọ | ≤0.002% | <0.002% |
| Mmiri (nke KF) | 2.20% ~ 2.70% | 2.46% |
| Sulfated Ash | ≤0.10% | <0.10% |
| Nyocha | 97.5% ~ 102.0% (Ihe na-eme Anhydrous) | 100.2% |
| Ihe mgbaze fọdụrụnụ | ||
| Methanol | ≤0.30% | 0.001% |
| Acetone | ≤0.50% | 0.001% |
| Isopropanol | ≤0.50% | 0.04% |
| Dichloromethane | ≤0.06% | Ọ dịghị |
| Toluene | ≤0.089% | 0.003% |
| Mmechi: Na-agbaso EP7.0. | ||
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Paroxetine Hydrochloride Hemihydrate (CAS: 110429-35-1) bụ otu n'ime ike kachasị ike na nhọrọ nke ndị na-emechi ihe nchịkwa serotonin (SSRI);antidepressant.Ọ bụ ihe nrụpụta phenylpiperidine, bụ ihe na-egbochi nnabata nke ST (serotonin transporter/5-HT).Ọ na-eme site na ijikọ na ST (onye na-ebugharị serotonin / SERT) nwere njikọ dị elu (Ki = 05 nM).Antidepressant na anxiolytic na vivo.Enwere ike iji Paroxetine hydrochloride na-agwọ ịda mbà n'obi, nke bụ ọgwụ ọhụrụ antidepressant.Enwere ike iji ya na-agwọ ọgụ ụjọ, nsogbu nchekasị zuru oke, nsogbu nchekasị nke ọha mmadụ, nsogbu uche na-adịghị mma (OCD), ehighị ụra nke ọma, ọrịa premenstrual syndrome, ejaculation akaghi aka na ọrịa ndị ọzọ, na-enwe mmetụta dị mma na-agwọ ọrịa na obere mmeghachi omume ọjọọ.Na-agwọ ụdị ịda mbà n'obi niile.Gụnyere ịda mbà n'obi nwere nchekasị na ịda mbà n'obi na-emeghachi omume.Mgbaàmà nke ịda mbà n'obi na-emekarị: ike ọgwụgwụ, nsogbu ụra, enweghị mmasị na obi ụtọ na ihe omume kwa ụbọchị, enweghị agụụ.Mgbe emechara mmetụta ọgwụgwọ ahụ, ọ nwere ike igbochi nlọghachi nke ịda mbà n'obi.
