Perindopril Erbumine CAS 107133-36-8 Ịdị Ọcha>99.5% (HPLC) ACE Inhibitor API Ụlọ ọrụ dị elu
| Aha Chemical | Perindopril erbumine |
| Ụdị okwu | Nnu perindopril tert-Butylamine;Aceon;(2S,3aS,7aS) -1-[(2S) -2-[[(1S) -1- (Ethoxycarbonyl) butyl] amino] -1-oxopropyl] octahydro-1H-indole-2-carboxylic acid tert-butylamine nnu |
| Nọmba CAS | 107133-36-8 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C19H32N2O5.C4H11N |
| Ibu molekụla | 441.61 |
| Ebe Na-agbaze | 126.0 ~ 128.0 ℃ |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ntụ ntụ kristal na-acha ọcha ma ọ bụ gbanyụọ |
| njirimara | IR;HPLC |
| Ntụgharị pụrụ iche [α]D20 | -66.0°~-69.0° |
| Ihe ndị na-adịghị ọcha A | ≤0.25% |
| Ihe adịghị ọcha I | ≤0.10% |
| Ihe adịghị ọcha amabeghị | ≤0.10% |
| Ihe adịghị ọcha E | ≤0.40% |
| Ihe ndị na-adịghị ọcha B | ≤0.30% |
| Ihe adịghị ọcha F | ≤0.20% |
| Ihe adịghị ọcha H | ≤0.20% |
| Ihe adịghị ọcha amabeghị | ≤0.10% |
| Mgbakọta adịghị ọcha | <0.50% |
| Ọdịnaya Mmiri | ≤1.00% |
| Ihe fọdụrụ na mgbanye | ≤0.10% |
| Ọla dị arọ | ≤20ppm |
| Ụzọ ịdị ọcha / nyocha | > 99.5% (HPLC) |
| Ihe ndị emetụtara | Zute nkọwapụta ahụ |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | API;ihe mgbochi ACE;Antihypertensive |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Perindopril Erbumine (CAS: 107133-36-8), makwaara dị ka Perindopril tert-Butylamine nnu, bụ ihe mgbochi ACE siri ike nke a na-eji agwọ ọbara mgbali elu, nkụda obi ma ọ bụ ọrịa akwara obi kwụsiri ike.Mgbochi nke enzyme a na-egbochi guzobe angiotensin II site na angiotensin I, nke na-egbochikwa vasoconstriction nke angiotensin II kpatara.Perindopril Erbumine bụ ihe na-arụ ọrụ ogologo oge nke angiotensin na-agbanwe enzyme (ACE) inhibitor (uru IC50 nke 10 μM).Kpọmkwem, Perindopril Erbumine bụ prodrug ọnụ nke Perindoprilat, onye na-egbochi ACE nwere uru IC50 nke 1.9 nM.
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