Pirfenidone CAS 53179-13-8 ịdị ọcha ≥99.0% IPF
Nyefee na ịdị ọcha dị elu, mmepụta azụmahịa
Aha Chemical: Pirfenidone
Nọmba: 53179-13-8
| Aha Chemical | Pirfenidone |
| Ụdị okwu | Perfenidone;5-Methyl-1-Phenylpyridine-2 (1H) -otu;PFD;S-7701;AMR-69 |
| Nọmba CAS | 53179-13-8 |
| Nọmba CAT | RF-API108 |
| Ọnọdụ Ahịa | Dị na ngwaahịa |
| Usoro ihe omimi | C12H11NO |
| Ibu molekụla | 185.22 |
| Ebe Na-agbaze | 96.0 ruo 97.0 ℃ |
| Solubility | Soluble na DMSO |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ọcha na-acha odo odo kristal ntụ ntụ |
| njirimara | IR |
| Ịdị ọcha | ≥99.0% |
| Ọnwụ na ihicha | ≤0.50% |
| Sulfated Ash | ≤0.20% |
| Otu adịghị ọcha | ≤0.50% |
| Mgbakọta adịghị ọcha | ≤1.0% |
| Ọla dị arọ | ≤20ppm |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | API, Fibrosis Pulmonary Idiopathic (IPF) |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Pirfenidone (CAS: 53179-13-8) dị n'ime otu ọgwụ a na-akpọ antifibrotic agents.Pirfenidone egosipụtala ọrụ n'ọtụtụ ọnọdụ fibrotic, gụnyere nke ngụgụ, akụrụ na imeju.Ọ na-emetụta usoro ahụ ji alụso ọrịa ọgụ nke ahụ gị ma belata ọnụọgụ fibrosis (scarring) na ngụgụ.Pirfenidone bụ otu n'ime ọgwụ abụọ akwadoro na Canada iji gwọọ Fibrosis Pulmonary Idiopathic (IPF).Pirfenidone bụ ihe mgbochi maka mmepụta TGF-β na TGF-β na-akpali mmepụta nke collagen, na-ebelata mmepụta nke TNF-α na IL-1β, ma nweekwa ihe mgbochi fibrotic na mgbochi mkpali.Ebu ụzọ kwado ya na Japan maka ọgwụgwọ ndị ọrịa na-arịa ọrịa pulmonary pulmonary fibrosis mgbe ule ụlọ ọgwụ gasịrị, n'okpuru aha ahia nke Pirespa nke Shionogi, na 2008. A kwadoro ya maka iji ya na European Union na 2011, na Canada na 2012, na na United States na October 2014.
