Posaconazole CAS 171228-49-2 API Ụlọ ọrụ Triazole Antifungal Agent High Quality

Nkọwa dị mkpirikpi:

Aha: Posaconazole

OZI: 171228-49-2

Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ

Nyocha: 98.0% ~ 102.0%

Posaconazole bụ Triazole Antifungal Agent

API Ogo dị elu, mmepụta azụmahịa

Kpọtụrụ: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Zitere anyị email

Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Nbunye ụlọ ọrụ Posaconazole metụtara Intermediates, Mmepụta Azụmahịa
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4- (4- (4-hydroxyphenyl) piperazin-1-yl) phenyl) carbamate CAS 184177-81-9
1- (4-Aminophenyl) -4- (4-hydroxyphenyl) piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2- (phenylmethoxy) propyl] hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+) -Tartrate CAS 87-91-2

Njirimara kemịkalụ:

Aha Chemical	Posaconazole
Ụdị okwu	POS;SCH 56592;4-[4-[4-[4-[[(3R,5R) -5- (2,4-Difluorophenyl) -5- (1,2,4-triazol-1-ylmethyl) oxolan-3-yl] methoxy]phenyl] piperazin-1-yl] phenyl] -2-[(2S,3S) -2-hydroxypentan-3-yl] -1,2,4-triazol-3-otu
Nọmba CAS	171228-49-2
Nọmba CAT	RF-API77
Ọnọdụ Ahịa	Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms
Usoro ihe omimi	C37H42F2N8O4
Ibu molekụla	700.78
Njupụta	1.36 g/cm3
Solubility	Soluble na DMSO, Na-adịghị edozi na Mmiri
Ọnọdụ mbupu	Ebugara n'okpuru okpomọkụ gburugburu
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ
njirimara A	IR: Ụdị nnabata infrared nke ngwaahịa kwesịrị ịdị na nke ihe ntụnyere aka
njirimara B	Oge njide HPLC yiri ihe ntụaka
Ebe Na-agbaze	167.0 ~ 171.0 ℃
Ntụgharị pụrụ iche [a]20	-24.0° ~ -28.0° (C=1, CHCL3)
Mmiri (KF)	≤1.0%
Ihe fọdụrụ na mgbanye	≤0.10%
Ihe ndị emetụtara
HT 909-24	≤0.20%
Ọdịghị ọcha nke Onye ọ bụla	≤0.10%
Mgbakọta adịghị ọcha	≤1.0%
Ihe mgbaze fọdụrụnụ
Methanol	≤3000ppm
Methyl tert-Butyl Ether	≤5000ppm
Isopropanol	≤5000ppm
Dimethyl sulfoxide	≤5000ppm
Dichloromethane	≤600ppm
Nyocha	98.0% ~ 102.0% (gbakọọ na nke a mịrị amị)
Ọla dị arọ	≤10ppm
Isomer	Enantiomer ≤0.10%
	Ọdịghị ọcha nke onye ọ bụla ≤0.10%
	Mkpokọta adịghị ọcha ≤1.0%
Nlele ọkọlọtọ	Ụkpụrụ ụlọ ọrụ;USP;BP;EP Standard
Ojiji	API, Triazole Antifungal Agent

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

Ajụjụ:

Ngwa:

Posaconazole (CAS 171228-49-2), bụ nnukwu ụdịdị dị iche iche, ọgbọ nke abụọ, triazole compound nwere ọrụ antifungal, nke ewepụtara na UK, bụ onye kachasị ọhụrụ na klas azole nke ndị na-ahụ maka ọgwụ nje iji rute n'ahịa ahụ.A na-egosi ya maka ọgwụgwọ na mgbochi nke ọrịa fungal dị iche iche, gụnyere aspergillosis, fusariosis, chromoblastomycosis, mycetoma, na coccidiomycosis na ndị ọrịa na-anabataghị, ma ọ bụ na-anabataghị ọgwụgwọ ọkọlọtọ na amphotericin B na / ma ọ bụ itraconazole.Na US, a kwadoro ya maka prophylaxis nke ọrịa Aspergillus na Candida na-efe efe na ndị ọrịa dị afọ 13 bụ ndị nọ n'ihe ize ndụ nke ịmalite ọrịa ndị a n'ihi enweghị mgbochi mgbochi.Ọzọkwa, a kwadoro ya maka ọgwụgwọ nke oropharyngeal candidiasis.Posaconazole nwere ọrụ dị iche iche gbasaara karịa ndị ọzọ so na azole antifungals.Na mgbakwunye na ọrụ siri ike megide ọrịa refractory nke aspergillosis na Candida na-eguzogide fluconazole, ọ na-egosipụta ọrụ megide Zygomycetes.Posaconazole bụ ọgwụ antifungal triazole nke Schering-Plough na-ere na United States n'okpuru aha ahia Noxafil.