Posaconazole Intermediate POA CAS 149809-43-8 Ụlọ ọrụ dị elu
Nbunye ụlọ ọrụ Posaconazole metụtara Intermediates, Mmepụta Azụmahịa
Posaconazole CAS 171228-49-2
Posaconazole Intermediate POA CAS 149809-43-8
Phenyl (4- (4- (4-hydroxyphenyl) piperazin-1-yl) phenyl) carbamate CAS 184177-81-9
1- (4-Aminophenyl) -4- (4-hydroxyphenyl) piperazine CAS 74853-08-0
2-[(1S,2S)-1-Ethyl-2- (phenylmethoxy) propyl] hydrazinecarboxal CAS 170985-85-0
Diethyl L-(+) -Tartrate CAS 87-91-2
Aha | Posaconazole Intermediate POA |
Ụdị okwu | (5R-cis) -Toluene-4-sulfonic acid 5- (2,4-difluorophenyl) -5- (1H-1,2,4-triazol-1-yl) methyltetrahydrofuran-3-ylmethyl ester;(3S,5R) -5- (2,4-Difluorophenyl) -5-[(1H-1,2,4-triazol-1-yl) methyl] oxolan-3-ylmethyl p-Toluenesulfonate |
Nọmba CAS | 149809-43-8 |
Nọmba CAT | RF-PI291 |
Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilogram |
Usoro ihe omimi | C21H21F2N3O4S |
Ibu molekụla | 449.47 |
Njupụta | 1.40 |
Ọnọdụ mbupu | Ebugara n'okpuru okpomọkụ gburugburu |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha na-acha ọcha ntụ ntụ |
njirimara | IR dabere na ọkọlọtọ |
Ebe Na-agbaze | 100.0-102.0 ℃ |
Ntụgharị a kapịrị ọnụ [a]20/D | -40.0° ruo -48° (C=1, CHCl3) |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
Ihe ndị emetụtara | |
Nnukwu adịghị ọcha | ≤0.40% |
POA-Enantiomer | ≤0.10% |
POA-Diastereomer | ≤0.20% |
Ọdịghị ọcha n'otu n'otu amabeghị | ≤0.20% |
Mgbakọta adịghị ọcha | ≤1.0% |
Ịdị ọcha | ≥99.0% |
Nyocha | 98.0% ~ 102.0% (ihe na-ekpo ọkụ) |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ọkara nke Posaconazole (CAS 171228-49-2) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe pụọ na ọkụ, mmiri mmiri na ọrịa nje.
(5R-cis) -Toluene-4-sulfonic acid 5- (2,4-difluorophenyl) -5- (1H-1,2,4-triazol-1-yl) methyltetrahydrofuran-3-ylmethyl ester (CAS 149809-43). -8) bụ etiti nke Posaconazole (CAS 171228-49-2).Posaconazole bụ ihe antifungal nke triazole nke na-egbochi njikọ nke ergosterol site na igbochi enzyme lanosterol 14α-demethylase na nchịkọta nke methylated sterol precursors, nke nwere ike igbochi 14α-demethylase karịa itraconazole.