Pyridine-3-Sulfonyl Chloride CAS 16133-25-8 Ịdị ọcha ≥98.5% (GC) Vonoprazan Fumarat Ụlọ ọrụ etiti
Nyefee Vonoprazan Fumarate na Intermediate emetụtara
5- (2-Fluorophenyl) pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Aha Chemical | Pyridine-3-sulfonyl chloride |
| Ụdị okwu | 3-Pyridinesulfonyl chloride;3-Pyridylsulfonyl chloride;m-Pyridinesulfonyl chloride;Piperidine-3-sulfonylchloride |
| Nọmba CAS | 16133-25-8 |
| Nọmba CAT | RF-PI540 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C5H4ClNO2S |
| Ibu molekụla | 177.61 |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Mmiri mmiri na-acha odo odo na-enweghị agba |
| Ụzọ ịdị ọcha / nyocha | ≥98.5% (GC) |
| Ebe esi nri | 110.0 ~ 112.0 ℃ / 2mm Hg |
| Otu adịghị ọcha | ≤0.50% |
| Mgbakọta adịghị ọcha | ≤1.5% |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Ọkara nke Vonoprazan Fumarate (CAS: 1260141-27-2) |
ngwugwu: Kalama, 25kg / gbọmgbọm, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Pyridine-3-Sulfonyl Chloride (CAS: 16133-25-8) bụ etiti nke Vonoprazan Fumarate (CAS: 1260141-27-2).Vonoprazan Fumarate, nke Takeda na Otsuka chọtara ma mepụta, PMDA nke Japan kwadoro na Disemba 2014, a na-egosikwa ya maka ọgwụgwọ ọnya afọ, ọnya duodenal na reflux esophagitis.Vonoprazan fumarate nwere usoro ihe omume nke a na-akpọ potassium-competitive acid blockers, bụ nke na-egbochi njikọ nke ion potassium na H +, K+-ATPase (nke a makwaara dị ka mgbapụta proton) na njedebe ikpeazụ nke secretion acid gastric na cell parietal gastric.Vonoprazan anaghị egbochi ọrụ Na +, K+-ATPase ọbụna na mkpokọta 500 ugboro dị elu karịa nke ụkpụrụ IC50 ha megide gastric H +, K+-ATPase ọrụ.Ọzọkwa, ọgwụ ahụ adịghị emetụta steeti secretory gastric, n'adịghị ka PPI.
