(R) -Lansoprazole Dexlansoprazole CAS 138530-94-6 Assay 98.0 ~ 102.0% (HPLC) Ụlọ ọrụ

Nkọwa dị mkpirikpi:

Aha ọgwụ: (R) -Lansoprazole

Nkọwa okwu: Dexlansoprazole

CAS: 138530-94-6

Nyocha: 98.0 ~ 102.0% (HPLC, % w/w)

Ọdịdị: White ka Gbanyụọ-White Crystalline ntụ ntụ

E-Mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Njirimara kemịkalụ:

Aha Chemical (R) - Lansoprazole
Ụdị okwu R-(+) -Lansoprazole;Dexlansoprazole;2-[(R)-[3-Methyl-4- (2,2,2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -1H-benzimidazole;T 168390;TAK 390;Lansoprazole adịghị ọcha 14;Ihe ndị metụtara Dexlansoprazole 2;(R) -2-[[3-Methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-Benzimidazole;
Nọmba CAS 138530-94-6
Nọmba CAT RF-PI1916
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C16H14F3N3O2S
Ibu molekụla 369.36
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ
Solubility Soluble na Dimethylformamide, ọ fọrọ nke nta ka ọ bụrụ ihe a na-apụghị ịsacha na mmiri
Ịdị ọcha & Agba nke Ngwọta Na-emezu ihe achọrọ
njirimara IR Ụdị nnabata infrared kwesịrị ikwekọ na ihe ntụnyere aka
njirimara HPLC Oge njide nke isi kacha elu kwesịrị ikwekọ na nke ntụnyere aka
Ntụgharị akọwapụtara +142.0°~+149.0°
Ebe Na-agbaze ~ 140.0 ℃
Ọdịnaya Mmiri (KF) <1.00%
Ihe fọdụrụ na mgbanye <0.10%
Ihe adịghị ọcha emetụtara (HPLC)
Nitrogen Oxide <0.10%
Sulfone <0.40%
Sulfide <0.20%
Ọdịghị ọcha ọ bụla ọzọ <0.10%
Mgbakọta adịghị ọcha <0.60%
Ọcha anya (HPLC) > 99.5%
Nyocha 98.0 ~ 102.0% (HPLC,% w / w, na anhydrous ndabere, ihe mgbaze-free)
Ọla dị arọ <10ppm
Ihe mgbaze fọdụrụnụ  
Toluene <890ppm
n-Heptane <5000ppm
Endotoxin nke nje bacteria <2.5EU/mg
Nlele ọkọlọtọ Ụkpụrụ USP;Ndị China Pharmacopoeia
Ojiji API;Onye na-egbochi mgbapụta Proton na-arụ ọrụ ọnụ

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

1

Ajụjụ:

Ngwa:

(R) -Lansoprazole (CAS: 138530-94-6) bụ R enantiomer nke Lansoprazole, Lansoprazole (AG 1749) bụ onye na-eme ihe na-eme ka proton mgbapụta ọnụ na-egbochi afọ imepụta acid.Dexlansoprazole maka Lansoprazole dextroisomer, bụ ụdị mgbochi peptic ọnyá afọ ọgwụ maka nnọchi benzimidazole usoro, na molekụla Ọdịdị n'ime mmewere fluorine, nke abụọ proton mgbapụta inhibitors omeprazole mgbe.Dexlansoprazole nwere mmetụta nke igbochi secretion nke gastric acid, mmetụta ahụ dị mma karịa nke ọgwụ ndị ọzọ (Omeprazole, Pantoprazole, Rebela, Tetrazolium) nwere ike igbochi ọnya ọnya.Ọ dị elu karịa famotidine ma ọ bụ Omeprazole maka mmebi nke mmanya na-aba n'anya na-akpata mucosa gastric na ọnya duodenal bụ nke kpatara hypersecretion acid.Na mgbakwunye, ngwaahịa ahụ nwere mmetụta mgbochi Helicobacter pylori dị ka nkwadebe bismuth, a na-ejikwa ya maka reflux esophagitis na ọrịa Zhuo AI.Takeda Pharmaceuticals nwetara nkwado nke dexlansoprazole, usoro ntọhapụ abụọ nke (R) -isomer nke lansoprazole proton pump inhibitor (PPI) ugbua na ahịa, site na FDA na Jenụwarị 2009. Dexlansoprazole bụ capsule ntọhapụ na-egbu oge maka otu ụbọchị, ọgwụgwọ ọnụ. nke nrekasi obi jikọtara ya na symptomatic na-abụghị erosive gastroesophageal reflux ọrịa (GERD), ọgwụgwọ erosive esophagitis (EE) na mmezi nke gwọọ EE.

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