Rabeprazole Sodium CAS 117976-90-6 Ịdị ọcha> 99.5% (HPLC) Ụlọ ọrụ API
Ruifu Chemical Supply Rabeprazole Sodium Intermediates
Rabeprazole sodium CAS 117976-90-6
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Aha Chemical | Rabeprazole sodium |
Ụdị okwu | 2- ([4- (3-Methoxypropoxy) -3-Methylpyridin-2-yl] methylsulfinyl -1H-Benzo [d] imidazole;Pariprazole |
Nọmba CAS | 117976-90-6 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C18H20N3NaO3S |
Ibu molekụla | 381.42 |
Ebe Na-agbaze | 140.0 ~ 141.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | kristal edo edo ma ọ bụ ntụ ntụ na-acha ọcha ka ọ dị ntakịrị;Hygroscopic |
Spectrum infrared | Dabara na Ọdịdị |
Ọnụ ego nke Proton NMR Spectrum | Dabara na Ọdịdị |
ICP | Na-akwado Ngwakọta Sodium |
Solubility | Na-agbaze kpamkpam n'ime mmiri;Soluble nke ukwuu na Ethanol, Chloroform;Soluble na methanol |
pH | 9.5-12.0 |
Ọnwụ na ihicha | <1.00% |
Ọla dị arọ | <20ppm |
Ihe ndị emetụtara | (HPLC) |
adịghị ọcha A | <0.80% |
Ihe adịghị akọwapụtaghị | <0.20% |
Mgbakọta adịghị ọcha | <1.00% |
Ihe mgbaze fọdụrụnụ | (GC) |
Methylene chloride | <600ppm |
Ethanol | <5000ppm |
Isopropyl Ether | <5000ppm |
Acetone | <5000ppm |
Oke Microbial | |
Ọnụọgụ Aerobe | ≤1000CFU/g |
Akpụkpọ na Yist agụta | ≤100CFU/g |
E. Coli | Adịghị maka kwa gram |
Ụzọ ịdị ọcha / nyocha | > 99.5% (HPLC, ndabere akpọnwụ) |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | API maka mgbochi ọnya |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Rabeprazole Sodium (CAS: 117976-90-6) bụ proton pump inhibitor nke na-egbochi mmepụta gastric acid n'ime afọ.Ọ nwere ọtụtụ ọgwụgwọ eji eme ihe: njikwa ọnọdụ ndị gụnyere oke mmepụta gastric acid (dịka ọmụmaatụ Zollinger-Ellison syndrome), ọnọdụ nke acid gastric na-akawanye njọ (dịka ọnya afọ nke eriri afọ), yana ọnọdụ metụtara ikpughe ogologo oge na acid gastric (dịka ọmụmaatụ. Symptomatic gastroesophageal reflux ọrịa).Rabeprazole dịkwa uru n'akụkụ ọgwụgwọ ọgwụ nje maka ọgwụgwọ pathogen Helicobacter pylori, nke na-eme nke ọma na gburugburu acidic.Ya mere, Rabeprazole Sodium bụ FDA kwadoro maka ọgwụgwọ GERD symptomatic na ndị nọ n'afọ iri na ụma na ndị okenye, na-agwọ ọnya duodenal na ndị okenye, ikpochapụ Helicobacter pylori, na ọnọdụ hypersecretory pathologic.Rabeprazole Sodium na-egbochi mmepụta nke acid n'ime afọ site na igbochi gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) na elu nzuzo nke cell parietal gastric.