Rapamycin Sirolimus RAPA CAS 53123-88-9 Assay ≥98.5% API Factory High Purity
Onye nrụpụta nwere ịdị ọcha dị elu yana ogo kwụsiri ike
Aha ọgwụ: Rapamycin;Sirolimus;RAPA
Nọmba: 53123-88-9
Macrolide Immunosuppressive Agent
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Rapamycin |
Ụdị okwu | Sirolimus;RAPA;AY-22989 |
Nọmba CAS | 53123-88-9 |
Nọmba CAT | RF-API59 |
Ọnọdụ Ahịa | Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms |
Usoro ihe omimi | C51H79NO13 |
Ibu molekụla | 914.19 |
Ebe Na-agbaze | 183.0 ~ 185.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ kristal na-acha ọcha ma ọ bụ gbanyụọ |
njirimara A | Ụdịdị IR nke potassium bromide nkwadebe nke ihe nlele ahụ na-egosipụta maxima n'otu ogologo wavelength dị ka nke nkwadebe yiri nke ọkọlọtọ n'ime ụlọ. |
njirimara B | UV ụdịdị dị iche iche nke 95% ethanol nkwadebe nke ihe nlele na-egosipụta maxima na 267nm, 277nm, 288nm dị ka nke nkwadebe yiri nke ụkpụrụ ntụaka ụlọ. |
njirimara C | Oge njigide nke ọnụ ọgụgụ kasị elu maka trans-na cis-stereoisomers na chromatogram nke nkwadebe nyocha kwekọrọ na nke ahụ na chromatogram nke nkwadebe ọkọlọtọ, dị ka enwetara na nyocha. |
Ntụgharị anya | -147.0°~ -157.0° |
Ọnwụ na ihicha | ≤0.50% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
Ọdịghị ọcha nke Onwe Onye | ≤1.5% |
Mgbakọta adịghị ọcha | ≤2.0% (ewezuga Cis-Stereoisomer nke Sirolimus) |
Cis-Stereoisomer nke Sirolimus | ≤5.0% |
Ihe mgbaze fọdụrụnụ | |
Ethanol | ≤5000ppm |
Ethyl acetate | ≤5000ppm |
Cyclohexane | ≤5000ppm |
Acetone | ≤5000ppm |
Diethyl Ether | ≤5000ppm |
Nyocha | ≥98.5% (trans- na cis-stereoisomer nke sirolimus gbakọrọ na ndabere siri ike) |
Nlele ọkọlọtọ | Ndị China Pharmacopoeia (CP);Standardkpụrụ ụlọ ọrụ |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Rapamycin (Sirolimus; AY 22989) bụ onye na-arụ ọrụ autophagy, ụdị ọhụrụ nke macrolide immunosuppressive agent nwere mmetụta ọgwụgwọ dị mma, nsi dị ala, na enweghị nephrotoxicity.Enwere ike iji ya jikwaa ihe mgbochi nke akụkụ ahụ a na-atụgharị (karịsịa na ntugharị akụrụ) iji belata ịjụ ọgwụ mgbochi ọrịa mgbe a gbasasịrị ịwa ahụ.
Dee ozi gị ebe a ziga anyị ya