Remdesivir Intermediate CAS 1911578-98-7 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate

Nkọwa dị mkpirikpi:

Aha chemical: 2-Ethylbutyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl) -L-alaninate

OZI: 1911578-98-7

Ọdịdị: White ka Gbanyụọ-Ọcha ntụ ntụỊdị ọcha: ≥98.0%

Ọkara nke Remdesivir (CAS 1809249-37-3) COVID-19

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Onye nrụpụta Azụmahịa Remdesivir na ihe ndị metụtara ya nwere ogo dị elu
Remdesivir CAS 1809249-37-3
2-Ethyl-1-butanol CAS 97-95-0
Trimethylsilyl Cyanide CAS 7677-24-9
4-Nitrophenol CAS 100-02-7
2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate CAS 1911578-98-7
N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl] -L-Alanine 2-ethylbutyl ester CAS 1354823-36-1
(S) -2-Ethylbutyl 2-Aminopropanoate Hydrochloride CAS 946511-97-3
Metabolite Remdesivir (GS-441524) CAS 1191237-69-0
Remdesivir N-2 Intermediate CAS 1191237-80-5
2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
7-Bromopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS 937046-98-5
Pyrrolo[1,2-F][1,2,4]Triazin-4-Amine CAS 159326-68-8
4-Amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS 1770840-43-1

Njirimara kemịkalụ:

Aha Chemical	2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate.
Ụdị okwu	N-[(S) (2,3,4,5,6-pentafluorophenoxy) phenoxyphosphinyl] -L-Alanine 2-ethylbutyl ester;Remdesivir Intermediate;Remdesivir-001;Remdesivir adịghị ọcha 21
Nọmba CAS	1911578-98-7
Nọmba CAT	RF-PI303
Ọnọdụ Ahịa	Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms
Usoro ihe omimi	C21H27N2O7P
Ibu molekụla	495.38
Njupụta	1.2g / cm3
Ebe Na-agbaze	92.0 ~ 96.0 ℃ (ọkụ)
Ebe esi nri	356.7 ℃ na 760 mmHg
Ọnọdụ mbupu	Ebugara n'okpuru okpomọkụ gburugburu
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ọcha ka Gbanyụọ-Ọcha ntụ ntụ
Spectrum infrared	Dabara na Ọdịdị
Ịdị ọcha	≥99.0%
Ọnwụ na ihicha	≤0.50%
Otu adịghị ọcha	≤0.50%
Mgbakọta adịghị ọcha	≤1.0%
Ọla dị arọ	≤20ppm
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Ọkara nke Remdesivir (CAS 1809249-37-3)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

Ajụjụ:

Ngwa:

2-Ethylbutyl ((S)-(perfluorophenoxy) (phenoxy) phosphoryl) -L-alaninate (CAS 1911578-98-7) bụ isi etiti etiti dị elu na nkwadebe nke analogues metụtara Remdesivir.Remdesivir bụ ọgwụ monophosphoramidate nke analọgụ adenosine, bụ onye na-ahụ maka nje na-eme nyocha nke nwere ọrụ in vitro megide SARS coronavirus, MERS coronavirus na, n'oge na-adịbeghị anya, Covid-19.Emepụtara Remdesivir ka ọ bụrụ ọgwụgwọ maka ọrịa filovirus dị ka ọrịa Ebola ma ọ bụ nje Marburg.N'ikpeazụ, achọpụtara Remdesivir ka ọ na-egosi ọrụ mgbochi megide nje RNA ndị ọzọ nwere otu eriri dị ka nje syncytial iku ume, nje Nipah, nje Hendra, nje Junin, nje ahụ ọkụ Lassa na coronaviruses (gụnyere MERS na nje SARS).N'oge na-adịbeghị anya, a na-amụ ya dị ka ọgwụ na-ekwe nkwa maka ọgwụgwọ COVID-19 (nje virus ọhụrụ SARS).Remdesivir, nke Sayensị Gilead mepụtara, bụ prodrug adenosine nke na-abanye n'ụdị ya na-arụ ọrụ GS-441524 nke na-egbochi omume RNA polymerase nke RNA na-adabere na nje virus ma na-ezere nyocha site na viral exoribonuclease (ExoN), na-eme ka mbelata mmepụta RNA viral.