Rivaroxaban CAS 366789-02-8 Dị Ọcha> 99.5% (HPLC) Ụlọ ọrụ API Foto egosipụtara dị elu

Rivaroxaban CAS 366789-02-8 Dị Ọcha> 99.5% (HPLC) API Ogo dị elu

Nkọwa dị mkpirikpi:

Aha Chemical: Rivaroxaban

Nọmba ekwentị: 366789-02-8

Dị ọcha:> 99.5% (HPLC)

Ọdịdị: White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ntụ ntụ

API Ogo dị elu, mmepụta azụmahịa

E-Mail: alvin@ruifuchem.com

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Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Ndị nrụpụta Rivaroxaban emetụtara ndị nrụpụta:
(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0
4- (4-Aminophenyl) morpholin-3-otu CAS 438056-69-0
Rivaroxaban Intermediate CAS 446292-07-5
5-Chlorothiophene-2-Carboxylic Acid CAS 24065-33-6
5-Chlorothiophene-2-Carbonyl Chloride CAS 42518-98-9
Rivaroxaban API CAS 366789-02-8

Njirimara kemịkalụ:

Aha Chemical	Rivaroxaban
Ụdị okwu	(S) -Rivaroxaban;(S) -5-Chloro-N- ((2-oxo-3-- (4- (3-oxomorpholino) phenyl) -oxazolidin-5-yl) methyl) thiophene-2-carbox;BAY 59-7939
Nọmba CAS	366789-02-8
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C19H18ClN3O5S
Ibu molekụla	435.88
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ntụ ntụ ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ọcha
njirimara A	Ntinye infrared nke Rivaroxaban dabara na ụkpụrụ ntụnye aka
njirimara B	Oge njigide nke isi ọnụ ọgụgụ kachasị elu nke ngwọta ihe nlele kwekọrọ na nke usoro kwesịrị ekwesị ngwọta, dị ka enwetara na ịdị ọcha enantiomeric.
Enantiomeric ịdị ọcha	RVX RC01: ≤0.15%
Mmiri (KF)	≤0.50%
Sulfated Ash	≤0.10%
Ọla dị arọ	≤20ppm
Acid acid	≤5000ppm
Ihe ndị emetụtara (HPLC)
RVX RC02	≤0.15%
RVX RC03	≤0.15%
RVX RC04	≤0.15%
RVX RC05	≤0.15%
RVX RC06	≤0.15%
RVX RC07	≤0.15%
RVX RC08	≤0.15%
Ọdịghị ọcha nke Onye Ọ bụla ọzọ	≤0.10%
Mgbakọta adịghị ọcha	<0.50%
Ihe mgbaze fọdụrụ (GC)
Ethanol	≤5000ppm
Toluene	≤890ppm
Triethylamine	≤320ppm
Ụzọ ịdị ọcha / nyocha	> 99.5% (HPLC) (na-esighi ike)
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	API;Ọgwụ antithrombotic;Ihe mgbochi FXa

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.

Uru:

Ajụjụ:

Ngwa:

Rivaroxaban(CAS:366789-02-8) (Xarelto, Bayer) bụ ọgwụ mgbochi ọnụ.Ọ bụ ihe na-eme ihe ozugbo Xa inhibitor.A na-egosi Rivaroxaban maka 'ọgwụgwọ thrombosis miri emi na pulmonary embolism, na mgbochi nke thrombosis miri emi na-emegharị ugboro ugboro na pulmonary embolism na ndị okenye'.Maka ọgwụgwọ mbụ nke nnukwu akpa ume embolism, usoro akwadoro nke rivaroxaban bụ 15 mg ugboro abụọ kwa ụbọchị maka ụbọchị 21 mbụ na-esote 20 mg otu ugboro kwa ụbọchị maka ọgwụgwọ na-aga n'ihu na mgbochi nke thromboembolism venous ugboro ugboro.Ihe na-adịghị valvular Atrial Fibrillation (NVAF) iji gbochie ọrịa strok & embolism sistem.Ọgwụgwọ VTE siri ike & mgbochi nke VTE na-aga n'ihu [maka thrombosis miri emi (DVT) na embolism pulmonary (PE)].Mgbochi nke ihe omume thromboembolic venous (VTE) na ịwa ahụ ngbanwe hip ma ọ bụ ikpere (THR, TKR).