Roflumilast CAS 162401-32-3 Assay 99.0~101.0% API

Nkọwa dị mkpirikpi:

Aha Chemical: Roflumilast

OZI: 162401-32-3

Nnwale: 99.0 ~ 101.0% (gbakọọ na akpọnwụ akpọnwụ)

Ọdịdị: White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ White Crystalline ntụ ntụ

API PDE-4 Inhibitor COPD

Kpọtụrụ: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Zitere anyị email

Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Ruifu Chemical Supply Roflumilast Intermediates:
Roflumilast CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7

Njirimara kemịkalụ:

Aha Chemical	Roflumilast
Ụdị okwu	3- (Cyclopropylmethoxy) -N- (3,5-Dichloropyridin-4-yl)-4- (Ddifluoromethoxy) benzamide
Nọmba CAS	162401-32-3
Nọmba CAT	RF-PI2075
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C17H14Cl2F2N2O3
Ibu molekụla	403.21
Njupụta	1.471±0.060 g/cm3
Mmetụta	Okpomọkụ nwere mmetụta
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ
Solubility	Soluble n'efu na acetone, soluble na-adị ntakịrị na acetronitrile, nke na-esighi ike na ethanol anhydrous, ọ fọrọ nke nta ka ọ ghara ịsacha ya na mmiri.
Ebe Na-agbaze	157.0 ~ 162.0 ℃
Ọnwụ na ihicha	<0.50%
Ihe fọdụrụ na mgbanye	≤0.10%
Ọla dị arọ	≤10ppm
Chloride	≤0.01%
Nchọpụta A. UV	The wavelength nke kacha absorption kwesịrị na 213 ~ 251nm
njirimara B. IR	Ụdị nnabata ụdị IR nke sample dabara na nke ntụnyere aka
njirimara C.	Ọ na-egosi mmeghachi omume nke fluoride
Ihe ndị emetụtara
Otu adịghị ọcha	≤0.10%
Mgbakọta adịghị ọcha	<0.50%
Ihe mgbaze fọdụrụnụ
Tert-Butanol	<0.10%
Tetrahydrofuran	<0.072%
Toluene	<0.089%
N, N-Dimethylformamide	<0.088%
Nyocha	99.0 ~ 101.0% (Agbakọnyere na akpọnwụ akpọnwụ)
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	API;COPD

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

Ajụjụ:

Ngwa:

Roflumilast (CAS: 162401-32-3) bụ onye na-emechi ọnụ phosphodiesterase-4 (PDE-4) na-emechi ọnụ na ogige benzamide.Ọ bụ ụlọ ọrụ German Altana mepụtara ya na 1993 na ọ bụ naanị PDE-4 inhibitor nke a na-eji agwọ ọrịa nke akụkụ iku ume akwadoro maka ire ere.Roflumilast bụ ọgwụ mbụ n'ụdị ya iji lekwasị anya n'ọrịa na-adịghị ala ala obstructive pulmonary (COPD), na ọ bụkwa ọgwụ mgbochi mbufụt nke mbụ e mepụtara maka ndị ọrịa COPD.Ngwongwo ya pụrụ iche nwere ike inye aka ịhazi COPD: mgbe ejiri ya na bronchodilators na-agwọ ndị ọrịa COPD siri ike, Roflumilast nwere ike nweta uru nke ibelata mgbaàmà na ọnụ ọgụgụ na-arịwanye elu, si otú a na-eme ka ọ bụrụ ọgwụ mbụ na-elekwasị anya na ndị ọrịa nwere phenotype-spAecific COPD na-arịwanye elu. na mgbochi ikuku siri ike metụtara ụkwara na-adịghị ala ala na oke phlegm.E wezụga ịbụ ọgwụgwọ maka COPD siri ike, a pụkwara iji Roflumilast mee ihe iji gbochie ma na-agwọ ọrịa nke akụkụ okuku ume nke anụ ụlọ, ụkwara mucosa bronchitis, bronchitis asthmatic, na nnukwu bronchitis na sacculitis ikuku na-esonyere na nzuzo nzuzo nke akụkụ iku ume na-adịghị mma.