Rosuvastatin Calcium CAS 147098-20-2 Assay 98.5% ~ 102.0% API ụlọ ọrụ dị ọcha dị elu
Nye ya na ịdị ọcha dị elu yana ịdị mma kwụsie ike
Calcium nke rosuvastatin
Ọnọdụ: 147098-20-2
Mmepụta azụmahịa
Aha Chemical | Calcium nke rosuvastatin |
Ụdị okwu | ZD 4522 Calcium;(E) -6- [4- (4-Fluorophenyl) -6-Isoropyl-2- (Methyl-Methylsulfonyl-amino) pyrimidin-5-yl] -2,4-Dihydroxy-hex-5-Enoate;(6E) -7-{4- (4-Fluorophenyl)-6- (1-Methylethyl) -2-[Methyl (methylsulfonyl) amino] pyrimidin-5-yl}-3,5-Dihydroxyhept-6-Enoic Acid |
Nọmba CAS | 147098-20-2 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C44H54CaF2N6O12S2 |
Ibu molekụla | 1001.14 |
Ebe Na-agbaze | 122 ℃ |
Ọnọdụ mbupu | Ebugara n'okpuru okpomọkụ gburugburu |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka Gbanyụọ-Ọcha ntụ ntụ |
Ntụgharị akọwapụtara | +17.0° ~ +21.0° |
njirimara | A. Na-emezu ihe achọrọ B. UV: λmax=243nm C. IR: Yiri ihe ntụaka D. X-Ray: Yiri ihe ntụaka |
Chloride | ≤0.10% |
Sulfate | ≤0.10% |
Entiomer | ≤0.15% |
Ọdịnaya Calcium | 3.5% ~ 4.5% |
Ihe ndị emetụtara | |
Diastereomer | ≤0.15% |
5-Oxo-Rosucastatin | ≤0.15% |
Mmebi foto 1 | ≤0.15% |
Mmebi foto 2 | ≤0.15% |
Rosuvastatin bụ Lactone | ≤0.15% |
Rosuvastatin methyl Ester | ≤0.15% |
Rosuvastatin Isoamyl Ester | ≤0.15% |
Ọdịghị ọcha ọ bụla amabeghị | ≤0.10% |
Mgbakọta adịghị ọcha | ≤0.75% |
Mmiri (KF) | ≤3.0% |
Ọla dị arọ | ≤20ppm |
Isoamyl Bromide | ≤37.5pm |
Ihe mgbaze fọdụrụnụ | |
Ethyl Ether | ≤300ppm |
Acetonitrile | ≤410ppm |
Isoamyl mmanya | ≤5000ppm |
DMF | ≤880ppm |
Nyocha | 98.5% ~ 102.0% (gbakọọ na anhydrous ndabere) |
Nlele ọkọlọtọ | Ụkpụrụ ụlọ ọrụ;Ọkọlọtọ BP/USP/EP |
Ojiji | API |
ngwugwu: Kalama, gbọmgbọm, kaadiboodu drum, 25kg / gbọmgbọm, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè, mmiri mmiri
Calcium Rosuvastatin (CAS: 147098-20-2) bụ ọgwụ mgbochi hyperlipidemia bụ nke onye na-egbochi HMG-CoA reductase nke ụlọ ọrụ Britain AstraZeneca mepụtara nke ọma.Ọ dabara adaba maka ọgwụgwọ nke ọrịa lipid dị iche iche, gụnyere hypercholesterolemia, agwakọta agwa agwa agwa na hypertriglyceridemia dị mfe.A na-edepụta Calcium Rosuvastatin (CAS: 147098-20-2) dị ka ọgwụ statins kachasị ike na nke zuru oke nke batara n'ahịa maka iwetulata lipid na mmezi.N'iji ya na atorvastatin, nke a na-amata ugbu a na ọ na-arụ ọrụ kacha mma n'ụwa, ọ nwere mmetụta dị mma nke ibelata ọkwa LDL cholesterol yana ịbawanye ọkwa nke lipoprotein dị elu.Ọzọkwa, ọ nwere mma ndidi, ala mmetụta na pụrụ iche pharmacokinetic e ji mara na ọkara ndụ ihe dị ka 20h.