(S) -3-Aminoquinuclidine Dihydrochloride CAS 119904-90-4 Ịdị ọcha ≥99.0% ee≥99.0% Palonosetron Hydrochloride Intermediate
Nbubata Azụmahịa Palonosetron Hydrochloride na ihe ndị metụtara ya:
(S) -1,2,3,4-Tetrahydro-1-Naphthoic Acid CAS: 85977-52-2
(R) -1,2,3,4-Tetrahedro-1-Naphthoic Acid CAS: 23357-47-3
(S) -3-Aminoquinuclidine Dihydrochloride CAS: 119904-90-4
3-Quinuclidinone Hydrochloride CAS: 1193-65-3
1-Naphthoic Acid CAS: 86-55-5
Palonosetron Hydrochloride CAS: 135729-62-3 API
| Aha Chemical | (S)-3-Aminoquinuclidine Dihydrochloride |
| Ụdị okwu | (S)-(-)-3-Aminoquinuclidine 2 HCL |
| Nọmba CAS | 119904-90-4 |
| Nọmba CAT | RF-CC112 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C7H16Cl2N2 |
| Ibu molekụla | 199.12 |
| Njupụta | 1.24g / cm3 |
| Ebe Na-agbaze | 260 ℃ |
| Ebe esi nri | 470.4 ℃ na 760mmHg |
| Solubility na Mmiri | Soluble |
| Ọnọdụ mbupu | Ebugara n'okpuru okpomọkụ gburugburu |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ọcha na-acha odo odo kristal ntụ ntụ |
| IR | Absorption Spectra kwekọrọ na ntụaka |
| Mmeghachi omume chloride | Mmeghachi omume ziri ezi |
| Ịdị ọcha (HPLC) | ≥98.0% |
| Ọnwụ na ihicha | ≤0.50% |
| Ntụgharị pụrụ iche [α]D20 | -22.0°~ -26.0° (C=1, H2O) |
| Ọla dị arọ | ≤20ppm |
| Nchekwa | 5-8 ℃ Ikuku |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | Palonosetron Hydrochloride (CAS: 135729-62-3) Ndị etiti |
(S)-3-Aminoquinuclidine Dihydrochloride (CAS: 119904-90-4) Ụzọ sịntetik
ngwugwu: Kalama, Aluminom foil bag, Cardboard Drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Shanghai Ruifu Chemical Co., Ltd bụ onye na-emepụta ihe na onye na-ebubata (S) -3-Aminoquinuclidine Dihydrochloride (CAS: 2133-40-6) nwere oke mma.Ọ bụ n'etiti ọgwụ na-emekarị na njikọ nke Palonosetron Hydrochloride (CAS: 135729-62-3).
Palonosetron Hydrochloride (CAS: 135729-62-3) bụ ọgwụ na-egbochi ọgbụgbọ na ọgbụgbọ, nke bụ ụdị ọhụrụ nke na-ahọrọ nke ukwuu, onye na-anabata ihe nnabata 5-HT3 dị elu nke nwere ike igbochi vomiting reflex center peripheral neurons presynaptic 5-HT.Obi ụtọ nnabata na-emetụta sistemu ụjọ nke etiti na 5-HT.Obi ụtọ na-anabata ihe na-akpali akpali site na ọrụ nke akwara afferent vagal mgbe mpaghara, na-egbochi njedebe akwara vagus na eriri afọ, na-egbochi akara na 5-HT.Mpaghara ndị na-anabata ihe nwere ike ibelata ọgbụgbọ na ọgbụgbọ.Central Clinical maka ọgwụgwọ nnukwu emetogenic chemotherapy butere ọgbụgbọ na ọgbụgbọ na-egbu oge.N'ihi mmetụta ọgwụgwọ dị elu ya, obere mmetụta dị n'akụkụ, ogologo oge ọkara ndụ (ihe dị ka awa 40), obere usoro ọgwụgwọ, na ihe ndị ọzọ, ọ dọtara mmasị dị ukwuu.Na 1,2,3,4-tetrahydro-1-naphthoic acid dị ka ihe mmalite, nkewa, amination, mbelata, cyclization, nnu nke palonosetron hydrochloride granisetron.Nnyocha ụlọ ọgwụ gosiri na enwere ike iji palonosetron mee ihe n'enweghị nsogbu na corticosteroids, analgesics, antiemetics, antispasmodics na anticholinergic ọgwụ dị ka ihe mmalite, nkewa, amination, mbelata, cyclization, nnu nke palonosetron hydrochloride granisetron.
