Sevelamer Carbonate CAS 845273-93-0 API Ụlọ ọrụ dị ọcha dị elu
Onye nrụpụta nwere ịdị ọcha dị elu yana ịdị mma kwụsie ike
Aha Chemical: Sevelamer Carbonate
Nọmba: 845273-93-0
Sevelamer Carbonate bụ amine polymeric nke na-ejikọta phosphate ma jiri ya na-agwọ hyperphosphatemia na ndị ọrịa nwere ọrịa akụrụ na-adịghị ala ala.
API Ogo dị elu, mmepụta azụmahịa
Aha Chemical | Sevelamer Carbonate |
Ụdị okwu | 2-Propen-1-Amine Polymer nwere (Chloromethyl) Oxirane Carbonate |
Nọmba CAS | 845273-93-0 |
Nọmba CAT | RF-API28 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | (C3H7N) m.(C3H5ClO)n.(CH2O3) x |
Ibu molekụla | 211.64 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ruo ntụ ntụ edo edo |
njirimara A | Site na IR, Dakọtara na ọkọlọtọ ọrụ |
njirimara B | Kwesịrị ịbụ mmeghachi omume dị mma |
Chloride | ≤0.10% |
Ọnwụ na ihicha | ≤10.0% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
Nnwale solubility | Kwesịrị dabara na ọkọlọtọ |
Njikọ nke Phosphate | 3.0 ~ 7.0 mmol/g |
Oligomer soluble | ≤0.20% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Nlebara anya | Chebe ọkụ na Chekwaa n'ebe dị jụụ (≤5℃), ojiji kacha mma n'ime ọnwa isii |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
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Sevelamer carbonate bụ amine polymeric nke na-ejikọta phosphate ma jiri ya na-agwọ HYPERPHOSPHATEMIA na ndị ọrịa nwere ọrịa akụrụ.Sevelamer carbonate bụ resin mgbanwe anion, nwere otu ụdị polymeric dị ka sevelamer hydrochloride, nke carbonate na-anọchi chloride dị ka counterion.Ọ bụ ezie na counterions dị iche maka nnu abụọ ahụ, polymer n'onwe ya, ihe na-arụ ọrụ na-etinye aka na njikọ phosphate, bụ otu.Sevelamer carbonate ka amara chemically dị ka poly(allylamine-co-N, N'-diallyl-1,3diamino-2-hydroxypropane) carbonate nnu.Sevelamer carbonate bụ hygroscopic, mana ọ naghị agbaze na mmiri.Sevelamer Carbonate, polymer na-adịghị etinye ya bụ ihe nkedo phosphate nke ọnụ na ndị ọrịa nwere ọdịda akụrụ.A na-akọ na Sevelamer Carbonate dị obere ka ọ ga-ebute hypercalcemia, ọkwa dị ala nke PTH, na ọrịa akwara na-aga n'ihu na aortic calcification na ndị ọrịa hemodialysis karịa calcium nke dabeere na phosphate binders.
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