Sitagliptin CAS 486460-32-6 Ịdị ọcha> 99.0% (HPLC) API Ụlọ ọrụ dị ọcha dị elu
Nnweta Sitagliptin Phosphate Monohydrate Njikọta:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R) -3-Amino-4- (2,4,5-Trifluoro-Phenyl) -Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
| Aha Chemical | Sitagliptin |
| Ụdị okwu | (3R) -3-Amino-1-[3- (trifluoromethyl) -5,6,7,8-tetrahydro-1,2,4-triazolo [4,3-a] pyrazin-7-yl] -4- (2,4,5-trifluorophenyl) butan-1-otu |
| Nọmba CAS | 486460-32-6 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C16H15F6N5O |
| Ibu molekụla | 407.31 |
| Ebe Na-agbaze | 114.0 ~ 115.0 ℃ |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
| Nchọpụta nke HPLC | Oge njide nke Sample bụ Nkwekọrịta na ọkọlọtọ ntụaka |
| Ọnwụ na ihicha | <1.0% |
| Ihe fọdụrụ na mgbanye | <0.20% |
| Ihe ndị emetụtara | |
| Ọdịghị ọcha ọ bụla | <0.50% |
| Mgbakọta adịghị ọcha | <1.0% |
| Ịdị ọcha | > 99.0% (HPLC) |
| Enantiomeric ịdị ọcha | <0.50% |
| Ọla dị arọ | <20ppm |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | API;Ụdị II Ọrịa shuga mellitus |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Sitagliptin (CAS: 486460-32-6), dị ka ụdị ọgwụ antidiabetic ọhụrụ, Sitagliptin Phosphate nwere uru nke ịdabere na glucose, mmetụta hypoglycemic na-agafeghị oke, ụbara nzuzo na-enweghị hypoglycemia, na-ebelata agụụ nke ọma, na enweghị mmetụta ọ bụla dị ka ọgbụgbọ. vomiting, edema na ụbara ibu ahụ.Sitagliptin phosphate dị ka otu ọgwụgwọ ọgwụ na ndị ọrịa nwere ụdị ọrịa shuga II nwere ike belata ọkwa haemoglobin glycosylated (HbA1c).Ọ bụ dipeptidyl peptidase-4 (DPP-4) inhibitor, nke nwere ike imeziwanye ikike ahụ mmadụ iji belata ọkwa glucose ọbara dị elu.Merck & Co. mepụtara Sitagliptin ma kwado ya maka ojiji ahụike na United States na 2006.
