Sodium Valproate (VPA) CAS 1069-66-5 API Ụlọ ọrụ dị ọcha dị elu
Nbudata azụmahịa nke onye nrụpụta nwere ịdị ọcha dị elu yana ogo kwụsiri ike
Aha kemịkal: Sodium Valproate (VPA)
Ọkụ: 1069-66-5
Aha Chemical | Sodium Valproate |
Ụdị okwu | VPA;Valproic acid sodium nnu;Sodium 2-propylpentanoate |
Nọmba CAS | 1069-66-5 |
Nọmba CAT | RF-API14 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C8H15NaO2 |
Ibu molekụla | 166.20 |
Ebe Na-agbaze | 300 ℃ |
Njupụta | 1.0803 g/cm3 |
Mmiri Solubility | Soluble na Mmiri |
Ọnọdụ mbupu | N'okpuru ọnọdụ okpomọkụ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ, Hygroscopic |
njirimara | Spectrum infrared Site RT ntụnyere Mmeghachi omume nke Sodium nnu |
Solubility | Soluble nke ukwuu na mmiri, na-agbaze kpamkpam na Ethanol |
Acidity ma ọ bụ alkalinity | Dị ka EP Criterions si kwuo |
Dozie & Agba nke Ngwọta | Dị ka EP Criterions si kwuo |
Ọla dị arọ | ≤20ppm |
Sulfates | ≤200ppm |
Chloride | ≤200ppm |
Ọnwụ na ihicha | ≤2.0% |
Ọdịghị ọcha ọ bụla | ≤0.10% (GC) |
Mgbakọta adịghị ọcha | ≤0.30% (GC) |
Nyocha | 98.5% ~ 101.0% (Titration) |
Nlele ọkọlọtọ | European Pharmacopeia (EP) |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API) |
ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.
Sodium Valproate (CAS: 1069-66-5) bụ ihe na-egbochi mgbakasị ahụ na nke dị irè maka ịchịkwa ma enweghị ya yana isi ihe ọdịdọ tonic-clonic zuru oke.Valproic acid sodium salt (Sodium Valproate) bụ histone deacetylase (HDAC) inhibitor, na IC50 na nso nke 0.5 na 2 mM, na-egbochikwa HDAC1 (IC50, 400 μM), ma na-ebute proteasomal mmebi nke HDAC2.Valproic acid sodium nnu na-arụ ọrụ ngosi Notch1 ma na-egbochi mmụba n'ime obere sel cancer akpa ume (SCLC).A na-eji sodium Valproate (CAS: 1069-66-5) na-agwọ ọrịa epilepsy, ọrịa bipolar na mgbochi nke isi ọwụwa migraine.