Telmisartan CAS 144701-48-4 Ịdị ọcha> 99.5% (HPLC) Ụlọ ọrụ API

Nkọwa dị mkpirikpi:

Aha Chemical: Telmisartan

Ọkụ: 144701-48-4

Dị ọcha:> 99.5% (HPLC)

Ọdịdị: kristal na-acha ọcha ma ọ bụ na-apụ apụ

Angiotensin II nnabata antagonist

Ogo dị elu, mmepụta azụmahịa

E-Mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Njirimara kemịkalụ:

Aha Chemical Telmisartan
Ụdị okwu 4'-[4-Methyl-6- (1-Methyl-1H-Benzimidazol-2-yl) -2-Propyl-1H-Benzimidazol-1-yl] methyl] biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl]-2-Carboxylic Acid
Nọmba CAS 144701-48-4
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C33H30N4O2
Ibu molekụla 514.63
Ebe Na-agbaze 261.0 ~ 263.0 ℃
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ntụ ntụ kristal na-acha ọcha ma ọ bụ gbanyụọ
Isi Njirimara
Solubility Na-agbaze obere n'ime Methylene chloride, ntakịrị Souble na methanol, nke a na-apụghị ịsacha na mmiri, na-agbaze na 1M Solution Hydroxide
Nchọpụta IR Kwesịrị dakọtara na RS Infrared Absorption
HPLC njirimara Oge njide nke isi kacha elu kwesịrị ikwekọ na RS
Ụzọ ịdị ọcha / nyocha > 99.5% (HPLC)
Ọnwụ na ihicha <1.00%
Ihe fọdụrụ na mgbanye <0.10%
Ihe ndị emetụtara  
Ihe jikọrọ Telmisartan A <0.10%
Telmisartan Amide <0.10%
Njikọ njikọ Telmisartan B <0.10%
Telmisartan Diacid <0.10%
Telmisartan Tert-Butyl Ester <0.20%
Telmisartan adịghị ọcha amaghi ama <0.20%
Ọdịghị ọcha na-akọwapụtaghị <0.10%
Mgbakọta adịghị ọcha <1.00%
Ihe mgbaze fọdụrụnụ  
Methanol <0.30%
Ethanol <0.50%
Methylene dichloride <0.06%
n-Hexane <0.029%
Ethyl Ester nke acetic acid <0.50%
Toluene <0.089%
Acid acid <0.50%
Ọla dị arọ <10ppm
Arsenic (dị ka) <1.00pm
Ndu (Pb) <1.00pm
Cadmium (Cd) <1.00pm
Nha urughuru D90 abụghị ihe karịrị 15μm
Njupụta nnukwu (g/cc) 0.11-0.20
Njupụta enwetara (g/cc) 0.22-0.30
Ihe mgbochi pesticide fọdụrụnụ Ihe ọjọọ
Ngụkọta ọnụ ọgụgụ efere <1000cfu/g
Yist & ebu <100cfu/g
E. Coli Ihe ọjọọ
Salmonella Ihe ọjọọ
Nlele ọkọlọtọ Ụkpụrụ ụlọ ọrụ;USP 41 ọkọlọtọ
Ojiji API

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

1

Ajụjụ:

Ngwa:

Telmisartan (CAS: 144701-48-4) bụ ihe nrụpụta benzimidazole na onye na-anabata angiotensin II na-abụghị peptide nwere ihe mgbochi hypertensive.Telmisartan na-ahọrọ nke ọma na-emegide angiotensin II na-ejikọta ya na AT1 subtype receptor, nke dị na akwara vaskụla dị nro na gland adrenal.Antagonism na-ebute vasodilation ma na-egbochi mmepụta aldosterone nke angiotensin II, nke na-eduga n'ịbelata sodium na mmiri yana mmụba nke nsị potassium na-eduga na mbelata ọbara mgbali elu na-esote.Telmisartan bụ ụdị ọgwụ mgbali elu ọhụrụ, nke a na-eji naanị ya ma ọ bụ yana yana klaasị antihypertensive ndị ọzọ maka ọgwụgwọ ọbara mgbali elu.Ụlọ ọrụ German na-emepụta ọgwụ bụ Boehringer Ingelheim mere Telmisartan na mbụ;ọ nwetara patent German EP502,314 na 1991, a kwadoro nke mbụ ịbanye n'ahịa America na November 1998, wee banye German, Philippines, Australian, Belgium, British, na ahịa ndị ọzọ.

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