Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Ụlọ ọrụ na-emegide nje HIV Foto egosipụtara

Tenofovir Alafenamide Hemifumarate TAF CAS 1392275-56-7 API Ụlọ ọrụ na-emegide nje HIV dị elu

Nkọwa dị mkpirikpi:

Aha: Tenofovir Alafenamide Hemifumarate (TAF)

CAS: 1392275-56-7

Ọcha ka ọ fọrọ nke nta ka ọ bụrụ kristal ma ọ bụ ntụ ntụ kristal

Nyocha: 98.0% ~ 102.0%

Ọgwụ maka Tenofovir, eji na ọgwụgwọ ngwakọta maka ọgwụgwọ nje HIV-1

Ogo dị elu, mmepụta azụmahịa

Inquiry: alvin@ruifuchem.com

Zitere anyị email

Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Mgbakwunye Tenofovir metụtara azụmaahịa:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) phosphonate CAS 31618-90-3
(R)-(+) -Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl) adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) phosphonate CAS 3084-40-0
Adenine CAS 73-24-5

Njirimara kemịkalụ:

Aha Chemical	Tenofovir Alafenamide Hemifumarate
Ụdị okwu	TAF;GS-7340 Hemifumarate
Nọmba CAS	1392275-56-7
Nọmba CAT	RF-API91
Ọnọdụ Ahịa	Na Akụrụngwa, Mpụta Ihe ruru narị narị kilograms
Usoro ihe omimi	C25H33N6O9P
Ibu molekụla	592.55
Okpomọkụ nchekwa	Emechiri ya na nkụ, okpomoku ime ụlọ
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ọcha ka ọ fọrọ nke nta ka ọ bụrụ kristal ma ọ bụ ntụ ntụ kristal
Solubility	Soluble na Dimethylformamide, na methanol;Na-agbaze na mmiri na THF;Na-edozi ntakịrị na Acetonitrile na nke na-adịghị edozi na Dichloromethane na Toluene
njirimara A	Ụdị mmịpụta IR kwesịrị ịdị na ntụnye aka
njirimara B	Oge njide nke isi kacha elu nke ngwọta nlele na chromatogram mkpebi ọdịnaya kwekọrọ na nke ngwọta ntụaka.
njirimara C	Oge njigide Fumaric Acid nke kacha elu na mkpebi chromatogram nke ọdịnaya dabara na ọnụ ọgụgụ kacha elu nke ntụaka.
Ọdịnaya mmiri (nke KF)	≤1.0%
Ngwọta doo anya	N'ụzọ bụ isi, ọ nweghị ihe a na-ahụ anya na 2% (w/v) nke nkọwa Methanol Solution
Ihe mgbaze fọdụrụnụ
Acetonitrile	≤410ppm
Ethanol	≤5000ppm
Dichloromethane	≤600ppm
Toluene	≤890ppm
Ihe fọdụrụ na mgbanye	≤0.10%
Ọla dị arọ	≤20ppm
Ihe ndị emetụtara
PMPA	≤1.0%
Ngwakọta anhydride nke PMPA	≤0.75%
Otu Phenyl PPA	≤1.0%
Ọdịghị ọcha ọ bụla akọwapụtaghị	≤0.15%
Mgbakọta adịghị ọcha	≤2.0%
Isomer	≤1.0%
Ọdịnaya nke Fumaric Acid	9.0% ~ 13.0% (na anhydrous ndabere)
Oke Microbial
Ngụkọta ọnụ ọgụgụ microbial nke ikuku ikuku	≤1000CFU/g
Ngụkọta yist na ebu	≤100CFU/g
Escherichia Coli	Adịghị
Nyocha	98.0% ~ 102.0% (na anhydrous na ihe mgbaze-free ndabere)
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, kaadiboodu drum, 25kg / Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ọkụ, mmiri mmiri na ụmụ ahụhụ.

Uru:

Ajụjụ:

Ngwa:

Tenofovir Alafenamide Hemifumarate (TAF, GS-7340 hemifumarate), CAS 1392275-56-7, bụ nucleotide reverse transcriptase inhibitor (NRTIs) na a akwụkwọ akụkọ prodrug nke Tenofovir (TFV).Site na igbochi reverse transcriptase, TAF na-egbochi nje HIV ịba ụba ma nwee ike ibelata nje HIV n'ime ahụ.Tenofovir alafenamide bụ ọgwụ eji eme ihe, nke pụtara na ọ bụ ọgwụ anaghị arụ ọrụ.N'ime ahụ, a na-atụgharị tenofovir alafenamide na Tenofovir diphosphate (TFV-DP).Tenofovir Alafenamide Fumarate kwadoro na Nọvemba 2015 maka ọgwụgwọ HIV-1.