Tenofovir CAS 147127-20-6 Assay 98.0%~102.0% API Anti-HIV Factory
Mgbakwunye Tenofovir metụtara azụmaahịa:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) phosphonate CAS 31618-90-3
(R)-(+) -Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl) adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
Aha | Tenofovir |
Ụdị okwu | (R)-PMPA;(R) -9-(2-Phosphonomethoxypropyl)Adenine |
Nọmba CAS | 147127-20-6 |
Nọmba CAT | RF-API07 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C9H14N5O4P |
Ibu molekụla | 287.22 |
Ebe Na-agbaze | 276.0-280.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha kristal ntụ ntụ |
Usoro nyocha / nyocha | 98.0% ~ 102.0% (na anhydrous ndabere) |
Solubility | Na-agbaze ntakịrị na mmiri (0.1g na 100ml);Methanol na-adịghị edozi ya (0.01g na 100ml na karịa) |
njirimara UV | Mwepu na ihe dịka 261nm |
njirimara HPLC | Oge njide nke isi kacha elu na nlele ule kwesịrị dabara na nke ọkọlọtọ |
Sulfate ntụ ntụ | ≤1.5% |
Mmiri (KF) | ≤3.0% |
Ntụgharị ngwa anya akọwapụtara | -19.0° ~ -23.0° (na 25℃ anhydrous ndabere) |
PMPA Monoester adịghị ọcha | ≤1.5% (HPLC) |
Ọdịghị ọcha nke Single Max ọ bụla | ≤0.5% (HPLC) |
Mgbakọta adịghị ọcha | ≤3.0% (HPLC) |
Enantiomeric ịdị ọcha | ≤0.5% (HPLC) |
9-Propenyl Adenine | ≤75ppm (HPLC) |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè, mmiri mmiri.
Tenofovir (CAS: 147127-20-6) bụ acyclic phosphonate nucleotide analogue na reverse-transcriptase inhibitor (NtRTI).A na-eji ya dị ka ihe mgbochi nje HIV.Antiviral.Tenofovir disoproxil (Viread) bụ analog nke mbụ nucleotide nke American FDA kwadoro iji gwọọ nje HIV-1.Tenofovir bụ ọgwụ eji agwọ ọrịa ịba ọcha n'anya B yana mgbochi na ọgwụgwọ HIV/AIDS.Ọ na-egbochi ọrụ nke nje HIV reverse transcriptase site na ịsọ mpi na mkpụrụ osisi deoxyadenosine 5'-triphosphate, na-eme ka njedebe nke yinye DNA kwụsị.