Tenofovir Disoproxil Fumarate CAS 202138-50-9 Assay 98.0%~102.0% API Factory
Mgbakwunye Tenofovir metụtara azụmaahịa:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) phosphonate CAS 31618-90-3
(R)-(+) -Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl) adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) phosphonate CAS 3084-40-0
Adenine CAS 73-24-5
Aha Chemical | Tenofovir Disoproxil Fumarate |
Ụdị okwu | Tenofovir DF;Bis(POC) -PMPA Fumarate;GS 4331 Fumarate |
Nọmba CAS | 202138-50-9 |
Nọmba CAT | RF-API106 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C23H34N5O14P |
Ibu molekụla | 635.52 |
Ebe Na-agbaze | 113.0 ka 115.0 ℃ |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ntụ ntụ ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ọcha |
njirimara A | IR Spectrum kwekọrọ na ọkọlọtọ ntụaka |
njirimara B | Oge njigide nke isi kachasị elu site na ngwọta nlele dabara na nke ngwọta ọkọlọtọ, dị ka enwetara na ule ahụ. |
Nyocha | 98.0% ~ 102.0% (na anhydrous ndabere) |
Mmiri | ≤1.0% |
Fumaric acid | 17.5% ~ 19.0% |
Ihe fọdụrụ na mgbanye | ≤0.20% |
Ọla dị arọ | ≤20ppm |
Chloromethyl isopropyl Carbonate | ≤0.15% |
Ihe ndị emetụtara | |
Tenofovir | ≤0.15% |
Adenin | ≤0.15% |
Tenofovir Isoproxi Monoester | ≤1.0% |
Tenofovir Disoproxil Ethyl Ester | ≤0.15% |
Tenofovir Isopropyl Isoproxil | ≤0.30% |
Tenofovir Disoproxil Carbamate | ≤0.15% |
Tenofovir Disproxil | ≤0.15% |
Ọdịghị ọcha ọ bụla | ≤0.10% |
Mgbakọta adịghị ọcha | ≤2.0% |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | API |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.
Tenofovir Disoproxil Fumarate (CAS: 202138-50-9), prodrug nke tenofovir (Aha ahia: Viread) nke Gilead Sciences mepụtara, bụ ụdị ọgwụ antiretroviral nucleotide-analogues, na-arụ ọrụ site n'ime ihe dị ka ndị na-emechi transcriptase inhibitors[nRTIs] , nke na-egbochi reverse transcriptase, enzyme dị mkpa maka mmepụta nje na ndị bu nje HIV.Ekwesiri ighota na obu ihe nucleotide reverse transcriptase inhibitor nke ejirila mee ihe maka ọgwụgwọ nje HIV.Tenofovir Disoproxil Fumarate ka agbanwere ka ọ bụrụ tenofovir na vivo, nke bụ acyclic nucleoside phosphonate[nucleotide] analọgụ nke adenosine 5'-monophosphate.A na-ejikarị ya na ụdị ọgwụ ndị ọzọ eme ihe.Ọgwụ nje HIV enweghị ike ịgwọ HIV/AIDS, mana ijikọta ọgwụ nje HIV [nke a na-akpọ usoro nje HIV] kwa ụbọchị nwere ike inyere ndị nwere nje HIV aka ịdị ogologo ndụ, ahụike ka mma.Dabere na akwụkwọ FDA, tenofovir disoproxil fumarate nwekwara ike ịbụ maka ọgwụgwọ ọrịa ịba ọcha n'anya B [HBV] na-adịghị ala ala na ndị okenye na ụmụaka dị afọ 12 na karịa.