Tenofovir Disoproxil Fumarate CAS 202138-50-9 Assay 98.0%~102.0% API Factory

Nkọwa dị mkpirikpi:

Aha Chemical: Tenofovir Disoproxil Fumarate

OZI: 202138-50-9

Ọdịdị: White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ntụ ntụ

Nyocha: 98.0% ~ 102.0% (na anhydrous ndabere)

Nucleotide reverse transcriptase inhibitor eji agwọ HIV na ịba ọcha n'anya B.

Ogo dị elu, mmepụta azụmahịa

E-Mail: alvin@ruifuchem.com


Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Njirimara kemịkalụ:

Aha Chemical Tenofovir Disoproxil Fumarate
Ụdị okwu Tenofovir DF;Bis(POC) -PMPA Fumarate;GS 4331 Fumarate
Nọmba CAS 202138-50-9
Nọmba CAT RF-API106
Ọnọdụ Ahịa N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi C23H34N5O14P
Ibu molekụla 635.52
Ebe Na-agbaze 113.0 ka 115.0 ℃
Ụdị Ruifu Chemical

Nkọwapụta:

Ihe Nkọwapụta
Ọdịdị Ntụ ntụ ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ọcha
njirimara A IR Spectrum kwekọrọ na ọkọlọtọ ntụaka
njirimara B Oge njigide nke isi kachasị elu site na ngwọta nlele dabara na nke ngwọta ọkọlọtọ, dị ka enwetara na ule ahụ.
Nyocha 98.0% ~ 102.0% (na anhydrous ndabere)
Mmiri ≤1.0%
Fumaric acid 17.5% ~ 19.0%
Ihe fọdụrụ na mgbanye ≤0.20%
Ọla dị arọ ≤20ppm
Chloromethyl isopropyl Carbonate ≤0.15%
Ihe ndị emetụtara
Tenofovir ≤0.15%
Adenin ≤0.15%
Tenofovir Isoproxi Monoester ≤1.0%
Tenofovir Disoproxil Ethyl Ester ≤0.15%
Tenofovir Isopropyl Isoproxil ≤0.30%
Tenofovir Disoproxil Carbamate ≤0.15%
Tenofovir Disproxil ≤0.15%
Ọdịghị ọcha ọ bụla ≤0.10%
Mgbakọta adịghị ọcha ≤2.0%
Nlele ọkọlọtọ Standardkpụrụ ụlọ ọrụ
Ojiji API

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ.

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri.

Uru:

1

Ajụjụ:

Ngwa:

Tenofovir Disoproxil Fumarate (CAS: 202138-50-9), prodrug nke tenofovir (Aha ahia: Viread) nke Gilead Sciences mepụtara, bụ ụdị ọgwụ antiretroviral nucleotide-analogues, na-arụ ọrụ site n'ime ihe dị ka ndị na-emechi transcriptase inhibitors[nRTIs] , nke na-egbochi reverse transcriptase, enzyme dị mkpa maka mmepụta nje na ndị bu nje HIV.Ekwesiri ighota na obu ihe nucleotide reverse transcriptase inhibitor nke ejirila mee ihe maka ọgwụgwọ nje HIV.Tenofovir Disoproxil Fumarate ka agbanwere ka ọ bụrụ tenofovir na vivo, nke bụ acyclic nucleoside phosphonate[nucleotide] analọgụ nke adenosine 5'-monophosphate.A na-ejikarị ya na ụdị ọgwụ ndị ọzọ eme ihe.Ọgwụ nje HIV enweghị ike ịgwọ HIV/AIDS, mana ijikọta ọgwụ nje HIV [nke a na-akpọ usoro nje HIV] kwa ụbọchị nwere ike inyere ndị nwere nje HIV aka ịdị ogologo ndụ, ahụike ka mma.Dabere na akwụkwọ FDA, tenofovir disoproxil fumarate nwekwara ike ịbụ maka ọgwụgwọ ọrịa ịba ọcha n'anya B [HBV] na-adịghị ala ala na ndị okenye na ụmụaka dị afọ 12 na karịa.

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