tert-Butyl 4- (6-Nitropyridin-3-yl) piperazine-1-Carboxylate CAS 571189-16-7 Ịdị ọcha>98.0% (HPLC) Palbociclib Intermediate Factory

Nkọwa dị mkpirikpi:

Aha kemịkal: tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate

Ụdị okwu: 1-Boc-4-(6-Nitro-3-Pyridyl) piperazine

Nọmba: 571189-16-7

Dị ọcha:> 98.0% (HPLC)

Ọdịdị: Light Brown ka Brown Powder

Ọkara nke Palbociclib (CAS: 571190-30-2)

E-Mail: alvin@ruifuchem.com

Zitere anyị email

Nkọwa ngwaahịa

Ngwaahịa ndị emetụtara

Mkpado ngwaahịa

Nkọwa:

Ruifu Chemical Supply Palbociclib metụtara Intermediates:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H) -otu CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-otu CAS 1013916-37-4

Njirimara kemịkalụ:

Aha Chemical	tert-Butyl 4- (6-Nitropyridin-3-yl) piperazine-1-Carboxylate
Ụdị okwu	1-Boc-4- (6-Nitro-3-Pyridyl) piperazine;4- (6-Nitro-3-pyridinyl) -1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate
Nọmba CAS	571189-16-7
Nọmba CAT	RF-PI1850
Ọnọdụ Ahịa	N'ọkwa, Mpụta Ihe ruru Tọn
Usoro ihe omimi	C14H20N4O4
Ibu molekụla	308.33
Ụdị	Ruifu Chemical

Nkọwapụta:

Ihe	Nkọwapụta
Ọdịdị	Ìhè Brown ka Brown ntụ ntụ
Ụzọ ịdị ọcha / nyocha	> 98.0% (HPLC)
LCMS	Nkwekọrịta na Ọdịdị
Ọnwụ na ihicha	<1.00%
Mgbakọta adịghị ọcha	<2.00%
Nlele ọkọlọtọ	Standardkpụrụ ụlọ ọrụ
Ojiji	Ọkara nke Palbociclib (CAS: 571190-30-2)

Ngwungwu & Nchekwa:

ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ

Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri

Uru:

Ajụjụ:

Ngwa:

tert-Butyl 4- (6-nitropyridin-3-yl) piperazine-1-carboxylate (CAS: 571189-16-7) bụ etiti nke Palbociclib (CAS: 571190-30-2).Palbociclib (nke a makwaara dị ka nọmba ogige PD-0332991) bụ ọgwụ nnwale maka ọgwụgwọ ọrịa kansa ara nke Pfizer na-emepụta.Ọ bụ ihe mgbochi nhọrọ nke kinase nke dabere na cyclin CDK4 na CDK6.Palbociclib na-egbochi ọganihu okirikiri cell site na G1 ruo S site na igbochi CDK4/6-based retinoblastoma (RB) phosphorylation.A na-eji Palbociclibhas mee ihe maka ọgwụgwọ HER2 adịghị mma, estrogen receptor (ER) ọrịa cancer ara metastatic.