Tolvaptan CAS 150683-30-0 API Ịdị Ọcha>99.0% (HPLC)
Onye nrụpụta Tolvaptan na ndị etiti emetụtara:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Aha | Tolvaptan |
| Aha Chemical | N-[4- (9-chloro-6-hydroxy-2-azabicyclo[5.4.0] undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Nọmba CAS | 150683-30-0 |
| Nọmba CAT | RF-API101 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C26H25ClN2O3 |
| Ibu molekụla | 448,94 |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ntụ ntụ kristal na-acha ọcha ruo na-agbanyụọ |
| Ụzọ njirimara | IR, HPLC |
| Solubility | Soluble na Benzyl Alcohol na Methanol mana ọ naghị esiri ya ike na mmiri na Hexane |
| Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC) |
| Ebe Na-agbaze | 219.0 ~ 222.0 ℃ |
| Ọnwụ na ihicha | <0.50% |
| Ihe fọdụrụ na mgbanye | <0.10% |
| Otu adịghị ọcha | <0.50% |
| Mgbakọta adịghị ọcha | <1.00% |
| Ọla dị arọ | ≤20ppm |
| Ihe mgbaze fọdụrụnụ | Zute nkọwapụta ahụ |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | API;Ndị na-ahụ maka ọgwụ |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
Tolvaptan (CAS: 150683-30-0), makwaara dị ka OPC-41061, bụ onye na-ahọrọ, asọmpi arginine vasopressin receptor 2 antagonist eji agwọ hyponatremia (obere ọkwa sodium dị ala) jikọtara ya na nkụchi obi, cirrhosis, na ọrịa nke ọrịa obi. hormone antidiuretic na-ekwesịghị ekwesị (SIADH).Otsuka Pharmaceutical nwere ikikere tolvaptan n'okpuru aha ahia Samsca mgbe FDA kwadoro ọgwụ ahụ na Mee 2009. Tolvaptan egosila na ọ dị irè megide ọrịa akụrụ polycystic.N'ime ule 2004, tolvaptan a na-enye ya na diuretics ọdịnala ka achọpụtara na ọ na-abawanye mmịpụta nke oke mmiri ma melite ọkwa sodium n'ọbara n'ime ndị ọrịa nwere nkụda mmụọ na-enweghị iwepụta mmetụta ndị dị ka hypotension (ọbara mgbali elu) ma ọ bụ hypokalemia (mbelata ọkwa ọbara nke potassium).Ọgwụ ahụ egosipụtakwaghị mmetụta ọjọọ na ọrụ akụrụ.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-otu CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
