TTBB CAS 124750-51-2 Ịdị ọcha>96.0% (HPLC) Ụlọ ọrụ etiti Irbesartan
Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Tritil Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan Side Chain Hydrochloride CAS 151257-01-1
Aha Chemical | 5- (4'-Bromomethyl-1,1'-Biphenyl-2-yl) -1-Triphenylmethyl-1H-Tetrazole |
Ụdị okwu | TTBB;BBTT;5-[4'-Bromomethyl- (1,1'-Biphenyl) -2-yl] -1-Triphenylmethyltetrazole;N- (Triphenylmethyl) -5- (4'-Bromomethylbiphenyl-2-yl-) tetrazole;Olmesartan adịghị ọcha 12;Losartan Bromo N1-Trityl adịghị ọcha |
Nọmba CAS | 124750-51-2 |
Nọmba CAT | RF-PI1878 |
Ọnọdụ Ahịa | N'ahịa, Ike nrụpụta 150MT/Afọ |
Usoro ihe omimi | C33H25BrN4 |
Ibu molekụla | 557.48 |
Ebe Na-agbaze | 152.0 ~ 155.0 ℃ |
Njupụta | 1.28±0.10 g/cm3 |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ka ọ fọrọ nke nta ka ọ bụrụ ọcha ntụ ntụ |
Ụzọ ịdị ọcha / nyocha | > 96.0% (HPLC) |
Ọnwụ na ihicha | <0.50% |
adịghị ọcha A | <2.00% (HPLC) 5- (4-Methyl-1,1-Biphenyl-2-yl) -1-Triphenylmethyl-1H-Tetrazole |
adịghị ọcha B | <2.00% 5- (4'.4'-Dibromomethyl-1,1-Biphenyl-2-yl) -1-Triphenylmethyl-1H-Tetrazole |
Spectrum infrared | Dabara na Ọdịdị |
Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
Ojiji | Ndị etiti nke Irbesartan (CAS: 138402-11-6);Olmesartan Medoxomil adịghị ọcha |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
5- (4'-Bromomethyl-1,1'-Biphenyl-2-yl) -1-Triphenylmethyl-1H-Tetrazole (TTBB) (CAS: 124750-51-2) bụ etiti nke Irbesartan (CAS: 138402-11). -6).A na-eji Irbesartan maka ọgwụgwọ ọbara mgbali elu yana nephropathy na-arịa ọrịa mamịrị yana serum creatinine na proteinuria dị elu (> 300 mg / ụbọchị) na ndị ọrịa nwere ụdị ọrịa shuga 2 na ọbara mgbali elu.A na-ejikwa Irbesartan mee ihe dị ka onye na-ahụ maka ahịrị nke abụọ na ọgwụgwọ nke conges.Irbesartan bụ onye na-anabata angiotensin II antagonist nke a na-ejikarị maka ọgwụgwọ ọbara mgbali elu.Emepụtara ya site na Sanofi Research (nke bụ akụkụ nke Sanofi-Aventis ugbu a).Sanofi-Aventis na Bristol-Myers Squibb jikọrọ aka na-ere ya n'okpuru aha azụmaahịa Aprovel, Karvea na Avapro.