Valdecoxib CAS 181695-72-7 Ịdị ọcha>99.5% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Valdecoxib (CAS: 181695-72-7) nwere àgwà dị elu.Anyị nwere ike ịnye COA, nnyefe zuru ụwa ọnụ, obere na nnukwu ọnụọgụ dị.Ọ bụrụ na ị nwere mmasị na ngwaahịa a, biko ziga ozi zuru ezu gụnyere nọmba CAS, aha ngwaahịa, ọnụ ọgụgụ anyị.Please contact: alvin@ruifuchem.com
| Aha Chemical | Valdecoxib |
| Ụdị okwu | Bextra;SC 65872;Valus;Valz;4- (5-Methyl-3-Phenyl-4-Isooxazolyl) benzenesulfonamide;4- (5-Methyl-3-Phenyl-1,2-Oxazol-4-yl) benzenesulfonamide;4- (5-Methyl-3-Phenylisoxazol-4-yl) benzenesulfonamide. |
| Nọmba CAS | 181695-72-7 |
| Nọmba CAT | RF2833 |
| Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
| Usoro ihe omimi | C16H14N2O3S |
| Ibu molekụla | 314.36 |
| Ebe Na-agbaze | 162.0 ~ 167.0 ℃ |
| Ebe esi nri | 481.2± 55.0 ℃ |
| Njupụta | 1.303±0.06 g/cm3 |
| Mmetụta | Okpomọkụ nwere mmetụta |
| Mmiri Solubility | Na-adịghị edozi n'ime mmiri |
| Solubility | Soluble na Ethanol, Methanol |
| Okpomọkụ nchekwa. | Okpomọkụ ụlọ |
| Ụdị | Ruifu Chemical |
| Ihe | Nkọwapụta |
| Ọdịdị | Ọcha ma ọ bụ Gbanyụọ-Ọcha ntụ ntụ |
| Ụzọ ịdị ọcha / nyocha | > 99.5% (HPLC) |
| Ebe Na-agbaze | 162.0 ~ 167.0 ℃ |
| Mmiri (nke Karl Fischer) | <0.50% |
| Ihe fọdụrụ na mgbanye | <0.20% |
| Otu adịghị ọcha | <0.30% |
| Mgbakọta adịghị ọcha | <0.50% |
| Ọla dị arọ (dị ka Pb) | <20ppm |
| Spectrum infrared | Dabara na Ọdịdị |
| Ọnụ ego nke NMR Spectrum | Dabara na Ọdịdị |
| Nlele ọkọlọtọ | Standardkpụrụ ụlọ ọrụ |
| Ojiji | API, Ihe mgbochi COX-2 nke Abụọ |
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
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Uru?Ogo kachasị elu, ọnụ ahịa dị ọnụ ala, ọrụ ọkachamara na nkwado teknụzụ, nnyefe ngwa ngwa.
OgoNkwenye?Usoro njikwa mma siri ike.Ngwá ọrụ ọkachamara maka nyocha gụnyere NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, wdg.
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Nyocha ụlọ ọrụ?Nnabata nyocha ụlọ ọrụ.Biko mee oge oge tupu oge eruo.
MOQ?Enweghị MOQ.A na-anabata obere usoro.
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Synthesis omenala?Nwere ike ịnye ọrụ nhazi ahaziri iche ka ọ dabara mkpa nyocha gị nke ọma.
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Valdecoxib (CAS: 181695-72-7) bụ ọgbọ nke abụọ COX-2 inhibitor, mepụtara dị ka ihe na-esochi celecoxib maka ọgwụgwọ ọnụ otu ugboro kwa ụbọchị nke ọrịa ogbu na nkwonkwo, ọrịa ogbu na nkwonkwo nke okenye na mgbu nke ịhụ nsọ.Valdecoxib dị ihe dị ka 28,000-fold karịa nhọrọ megide mmadụ recombinant COX-2 karịa mmadụ recombinant COX-1.Na ex viva dum ọbara mmadụ, ụkpụrụ I&O megide COX-2 na COX-1 bụ 0.89 PM na 25.4 FM n'otu n'otu.N'ụdị anụmanụ, valdecoxib nwere ezigbo ọrụ ọnụ dị ka mgbochi mkpali.N'ime oke, valdecoxib ji ike gbochie carrageenan footpad edema na ọrịa ogbu na nkwonkwo na-ebute adjuvant.Valdecoxib bụ ọgwụ na-adịghị steroidal anti-inflammatory (NSAID) nke na-egosipụta mgbochi mkpali, analgesic na antipyretic Njirimara n'ụdị anụmanụ.Ọ bụ ihe mgbochi siri ike na nke nhọrọ nke njikọ prostaglandin bụ isi site na mgbochi nke COX-2.A na-eji Valdecoxib na-ebelata ụfọdụ mgbaàmà nke ọrịa ogbu na nkwonkwo (rheumatism) kpatara, dị ka mbufụt, ọzịza, isi ike, na mgbu nkwonkwo.A kwadoro Valdecoxib maka enyemaka nke ihe ịrịba ama na mgbaàmà nke ọrịa ogbu na nkwonkwo na ndị okenye rheumatoid ogbu na nkwonkwo na maka ọgwụgwọ nke isi dysmenorrhea.Akwụsịla Valdecoxib maka ọgwụgwọ mgbu mgbe ịwachara ahụ ozugbo na-esochi akwara akwara site na ịwa ahụ.
