Valsartan CAS 137862-53-4 Assay 98.0~102.0% API
Onye nrụpụta Valsartan na ndị etiti emetụtara:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1
Aha Chemical | Valsartan |
Ụdị okwu | N-Valeryl-N-[2'-(1H-tetrazol-5-yl) biphenyl-4-ylmethyl]-L-valine |
Nọmba CAS | 137862-53-4 |
Nọmba CAT | RF-API32 |
Ọnọdụ Ahịa | N'ọkwa, Mpụta Ihe ruru Tọn |
Usoro ihe omimi | C24H29N5O3 |
Ibu molekụla | 435.52 |
Ebe Na-agbaze | 116.0 ~ 117.0 ℃ |
Nkwụsi ike | Hygroscopic |
Ụdị | Ruifu Chemical |
Ihe | Nkọwapụta |
Ọdịdị | Ọcha ma ọ bụ Gbanyụọ-Ọcha ntụ ntụ;Na-enweghị isi, hygroscopic |
njirimara | Ụdịdị ụdịdị IR nke ihe nlele ahụ dabara na ọkọlọtọ ọkọlọtọ ụdịdị dị iche iche |
njirimara | Oge njide nke nnukwu ọnụ ọgụgụ dị elu na chromatogram nke nkwadebe nyocha ahụ kwekọrọ na nke nkwadebe ọkọlọtọ, dị ka enwetara na Assay. |
Solubility | Soluble na Methanol na Ethanol, Na-agbaze obere n'ime Ethylacetate, Soluble na Dichloromethane, Na-adịghị Anya na Mmiri |
Mmiri (KF) | ≤1.00% |
Mwepu (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
Ihe fọdụrụ na mgbanye | ≤0.10% |
Ọla dị arọ | ≤10ppm |
D-Valsartan | ≤1.00% (HPLC) |
Ihe ndị emetụtara (HPLC) | |
Butyryl-Valsartan | ≤0.20% |
Benzyl-Valsartan | ≤0.10% |
Otu adịghị ọcha amaghi ama | ≤0.10% |
Mgbakọta adịghị ọcha | ≤0.30% (Ewezuga D-Valsartan) |
Ihe mgbaze fọdụrụnụ (GC) | |
Methanol | ≤3000ppm |
Ethyl acetate | ≤5000ppm |
N, N-Dimethylformamide | ≤880ppm |
Toluene | ≤890ppm |
Ụzọ ịdị ọcha / nyocha | > 99.0% (HPLC gbakọrọ na anhydrous, ihe mgbaze na-enweghị ihe mgbaze) |
Nlele ọkọlọtọ | United States Pharmacopoeia (USP) |
Ojiji | Ngwakọta ọgwụ na-arụ ọrụ (API) |
Valsartan (CAS: 137862-53-4) Usoro mmepụta ihe
ngwugwu: Kalama, Aluminom foil bag, 25kg / Cardboard Drum, ma ọ bụ dị ka ndị ahịa chọrọ
Ọnọdụ Nchekwa:Na-echekwa n'ime akpa ndị a kpuchiri ekpuchi na ebe dị jụụ na nke kpọrọ nkụ;Chebe site na ìhè na mmiri mmiri
![1](https://a395.goodao.net/uploads/15.jpg)
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Shanghai Ruifu Chemical Co., Ltd. bụ onye na-emepụta ihe na onye na-ebubata Valsartan (CAS: 137862-53-4) nwere àgwà dị elu.Valsartan bụ onye na-emegide angiotensin II AT1 na-anabataghị peptide, Antihypertensive, nwere ikike maka nyocha ọbara mgbali elu na nkụda obi.
Mmetụta antihypertensive Valsartan siri ike karịa nke enalapril ma dabara adaba maka ọgwụgwọ ọbara mgbali elu, ọbara mgbali elu nke dị obere ma na-agafeghị oke, yana ọkachasị ọbara mgbali elu nke abụọ kpatara mmebi akụrụ.Ọ nwere ike belata proteinuria nke ukwuu maka ndị ọrịa nwere ọbara mgbali elu na-arịa ọrịa shuga ma ọ bụ ọrụ imeju nkịtị, ọ nwekwara ike ịkwalite uric acid na sodium urinary iji chebe akụrụ.Valsartan dịkwa mma maka ibelata ọnwụ nke obi maka ndị ọrịa nwere nnukwu ihe ize ndụ (ọdịda ventricular aka ekpe ma ọ bụ arụrụ arụ) mgbe ha nwesịrị nkụchi obi.
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Valsartan CAS 137862-53-4 Assay 98.0~102.0% API
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