Indomethacin CAS 53-86-1 Purity >99.5% (HPLC) Factory High Purity
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer and supplier of Indomethacin (CAS: 53-86-1) with high quality, commercial production. Welcomed to order.
Chemical Name | Indomethacin |
Synonyms | Indometacin; 1-(4-Chlorobenzoyl)-5-Methoxy-2-Methyl-3-Indoleacetic Acid |
CAS Number | 53-86-1 |
CAT Number | RF-PI1601 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C19H16ClNO4 |
Molecular Weight | 357.79 |
Solubility in Hot Methanol | Almost Transparency |
Water Solubility | Insoluble in Water |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White to Light Yellow Crystalline Powder |
Identification | Positive |
Melting Point | 158.0~162.0℃ |
Loss on Drying | ≤0.50% |
Residue on Ignition | ≤0.20% |
Single Impurity | ≤0.30% |
Total Impurities | ≤0.50% |
Heavy Metals | ≤20ppm |
Purity / Analysis Method | ≥99.5% (HPLC) |
Test Standard | Enterprise Standard |
Usage | API; Pharmaceutical Intermediates |
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
Indomethacin (CAS: 53-86-1) is a non-steroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling. It works by inhibiting the production of prostaglandins, molecules known to cause these symptoms. It is similar to ibuprofen (Motrin) and naproxen (Naprosyn, Aleve). Indomethacin works by reducing the production of prostaglandins. Prostaglandins are chemicals that the body produces and which cause the fever and pain that are associated with inflammation. Indomethacin blocks the enzymes that make prostaglandins (cyclooxygenase 1 and 2) and thereby reduces the levels of prostaglandins. As a result, fever, pain and inflammation are reduced. Indomethacin is available in an extended release form. The FDA first approved indomethacin in January 1965.