1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2 Aripiprazole Intermediate Purity >99,0% (HPLC)
Produsen Pasokan Perantara Aripiprazole Kanthi Kemurnian Tinggi
Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl) piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
Jeneng Kimia | 1-(2,3-Dichlorophenyl) piperazine Hydrochloride |
sinonim | 2,3-DCPP HCl;1-(2,3-Dichlorophenyl) piperazine HCl;Aripiprazole EP Impurity B;Senyawa sing gegandhengan karo Aripiprazole C |
Nomer CAS | 119532-26-2 |
Nomer CAT | RF-PI2268 |
Status Simpenan | Ing Simpenan, Kapasitas Produksi 30 MT / Wulan |
Formula Molekul | C10H12Cl2N2·HCl |
Bobot Molekul | 267.58 |
Titik Lebur | 245.0~247.0 ℃ |
Panyimpenan & Sensitivitas | Higroskopis.Suhu sekitar |
Kelarutan ing banyu | Larut ing banyu |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Putih utawa Off-White |
Kemurnian / Metode Analisis | > 99,0% (HPLC) |
Mundhut ing Pangatusan | <0,50% |
Sisa ing Ignition | <0,10% |
Impurity Tunggal | <0,50% |
Total Impurities | <1.00% |
Logam Berat (Pb) | ≤20ppm |
Spektrum Infrared | Conforms kanggo Struktur |
Test Standar | Standar Perusahaan |
Panggunaan | Perantara Aripiprazole (CAS: 129722-12-9) |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Higroskopis.Simpen adoh saka banyu / Kelembapan lan agen oksidasi.Tansah wadhah ditutup kanthi rapet lan lebokake ing kahanan sing adhem, garing lan duwe ventilasi sing apik.Simpen ing gas inert
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1-(2,3-Dichlorophenyl)piperazine Hydrochloride (CAS: 119532-26-2) minangka perantara penting saka Aripiprazole (CAS: 129722-12-9).Aripiprazole minangka jinis anyar saka turunan quinoline larut banget lipid, karakteristik efek farmakologis yaiku ora mung antagonis reseptor dopamin D 2 postsynaptic, nanging uga agonis reseptor dopamin D 2 presynaptic, uga bisa excite D 1, D 3, D 4 reseptor;nduweni efek ganda saka aktivasi parsial utawa antagonis reseptor ing reseptor 5-HT 1A;wis tumindak rampung antagonis ing reseptor 5-HT 2A.Fitur iki beda karo generasi pisanan, lan antipsikotik atipikal sing kalebu obat antipsikotik generasi kapindho, lan mulane diarani penstabil sistem dopamin utawa antipsikotik generasi katelu.Wiwit didol ing pasar, utamane digunakake ing skizofrenia klinis, perawatan gangguan afektif lan gangguan kejiwaan liyane.Miturut literatur, aripiprazole duweni efek sing signifikan marang gejala skizofrenia positif lan negatif lan kuatir, depresi, fungsi kognitif, nalika luwih aman.Uga dilapurake yen obat kasebut uga bisa nambani gangguan mental liyane, kayata gangguan swasana ati episode manic, pikun pikun sing ana gandhengane karo gangguan mental, gangguan kuatir, gangguan prilaku bocah, depresi.Saiki, Bristol-Myers Squibb lan Otsuka Pharmaceutical Company ngumumake yen Uni Eropa wis nyetujoni Abilify (aripiprazole) ing perawatan aplikasi dhaptar skizofrenia.
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