1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS 143254-82-4 Irinotecan Hydrochloride Intermediate Kemurnian Tinggi
Produsen Pasokan Irinotecan lan Intermediet sing gegandhengan:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
Jeneng Kimia | 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride |
Nomer CAS | 143254-82-4 |
Nomer CAT | RF-PI243 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C11H20Cl2N2O |
Bobot Molekul | 267.2 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Wêdakakêna putih utawa kuning cahya |
Assay | ≥98,0% (HPLC) |
Mundhut ing Pangatusan | ≤1,0% |
Logam abot | ≤20ppm |
Standar Tes | Standar Perusahaan |
Panggunaan | Intermediate saka Irinotecan Hydrochloride (CAS: 100286-90-6) |
Paket: Botol, tas Aluminium foil, Drum karton, 25kg / Drum, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya, kelembapan lan infestasi hama.
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Shanghai Ruifu Chemical Co., Ltd. minangka produsen lan pemasok 1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride (CAS: 143254-82-4) kanthi kualitas dhuwur.Iki minangka perantara biasane ing sintesis Irinotecan Hydrochloride (CAS: 100286-90-6), sawijining Inhibitor DNA Topoisomerase I.
lrinotecan hydrochloride, turunan semi-sintetik, larut banyu saka agen antikanker camptothecin sing kuat, diluncurake ing Jepang kanggo perawatan kanker paru-paru, ovarium, lan serviks.lrinotecan bisa nindakake aktivitas antitumor liwat inhibisi topoisomerase I, sawijining enzim seluler sing melu njaga struktur topografi DNA sajrone proses translasi, transkripsi, lan mitosis.lrinotecan ngalami de-esterifikasi in vivo kanggo ngasilake metabolit aktif, SN-38, sing 1000 kali luwih kuat tinimbang wong tuwa.Sanajan kurang beracun tinimbang camptothecin, sawetara pasien ing uji klinis nuduhake efek samping saka leukopenia, diare, mual, lan alopecia.