2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Kemurnian >99,5% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Pasokan Produsen, Kualitas lan Rega Kompetitif
Tipiracil Hydrochloride (CAS: 183204-72-0) Related Intermediates
6-(Klorometil)urasil CAS: 18592-13-7
6-(Hydroxymethyl)urasil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
| Jeneng Kimia | 2-Amino-1-Pyrroline Hydrochloride |
| sinonim | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
| Nomer CAS | 7544-75-4 |
| Nomer CAT | RF-PI1838 |
| Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
| Formula Molekul | C4H8N2·HCl |
| Bobot Molekul | 120.58 |
| Titik Lebur | 171,0 kanggo 175,0 ℃ |
| Sensitif | Higroskopis |
| Merk | Kimia Ruifu |
| Item | Spesifikasi | Asil |
| Penampilan | Bubuk Putih | Bubuk Putih |
| Kemurnian / Metode Analisis | > 99,5% (HPLC) | 99,8% |
| Impurity Tunggal paling gedhe | <0,50% | 0,09% |
| Kandungan Air (KF) | <0,50% | 0,45% |
| Proton NMR Spectrum | Conforms kanggo Struktur | Selaras |
| Test Standar | Standar Perusahaan | |
| Panggunaan | Intermediate Tipiracil Hydrochloride (CAS: 183204-72-0) | |
Paket: Botol, tas Aluminium foil, 25kg / Karton Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) minangka senyawa organik heterosiklik, sing bisa digunakake minangka perantara farmasi.2-Amino-1-Pyrroline Hydrochloride minangka perantara saka Tipiracil Hydrochloride (CAS: 183204-72-0) ing perawatan Kanker Rektal.Tipiracil Hydrochloride minangka inhibitor thymidine phosphorylase (TPase) sing kuat lan kompetitif kanthi nilai IC50 35 nM kanggo TPase plasenta manungsa.Iku selektif kanggo TPase tinimbang enzim metabolisasi pirimidin liyane (IC50s => 1 mM kanggo UPase, OPRTase, TK, lan DPDase).TPI nyegah fosforolisis lan degradasi trifluorothymidine, nukleosida sitotoksik, ing sampel tumor karsinoma payudara lan usus besar manungsa.Administrasi lisan TPI (12.5-50 mg / kg) ningkatake aktivitas anti-tumor trifluorothymidine ing model xenograft kanker perut AZ-521 tikus.Formulasi sing ngemot TPI wis digunakake kanggo perawatan kanker kolorektal metastatik.
