2-Chloro-5-Iodobenzoic Acid CAS 19094-56-5 Empagliflozin Intermediate Assay ≥99.0% (HPLC)
Pasokan Produsen, Kemurnian Tinggi, Produksi Komersial
Jeneng Kimia: 2-Chloro-5-Iodobenzoic Acid
CAS: 19094-56-5
Jeneng Kimia | 2-Chloro-5-Asam Iodobenzoat |
Nomer CAS | 19094-56-5 |
Nomer CAT | RF-PI438 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C7H4ClIO2 |
Bobot Molekul | 282.46 |
Kelarutan | Larut ing Metanol |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Kristal Putih utawa Kuning Pucat |
Metode Assay/Analisis | ≥99,0% (HPLC) |
Titik Lebur | 161.0~163.0 ℃ |
Mundhut ing Pangatusan | ≤0,50% |
Sisa ing Ignition | ≤0,20% |
Total Impurities | ≤1,0% |
Logam abot | ≤20ppm |
Sisa Solvent | Etanol |
Standar Tes | Standar Perusahaan |
Panggunaan | Intermediate Empagliflozin (CAS: 864070-44-0) |
2-Chloro-5-Iodobenzoic Acid (CAS 19094-56-5) Rute Sintetis
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
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2-Chloro-5-Iodobenzoic Acid (CAS: 19094-56-5) bisa digunakake minangka perantara farmasi ing sintesis Empagliflozin (CAS: 864070-44-0).Empagliflozin (jeneng dagang Jardiance) minangka inhibitor saka sodium glukosa co-transporter-2 (SGLT-2), lan nyebabake gula ing getih diekskresi dening ginjel lan dibuwang ing urin.Tanggal 1 Agustus 2014, Food and Drug Administration (FDA) resmi nyetujoni obat kasebut kanggo perawatan diabetes tipe 2, kanggo nambah lan ngontrol glukosa getih wong diwasa.Empagliflozin minangka obat pencegahan SGLT-2 katelu sing disetujoni dening FDA.Loro obat inhibitor SGLT-2 liyane, Canagliflozin lan Dapagliflozin, sing kalebu Johnson Pharmaceuticals, AstraZeneca lan Bristol-Myers Squibb, disetujoni dening FDA ing Nopember 2013 lan Januari 2014.
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