2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6 Linagliptin Intermediate Purity ≥99,0% (HPLC)
Produsen Pasokan Linagliptin lan Intermediet sing Gegandhengan:
Linagliptin CAS 668270-12-0
Linagliptin Induk Nukleus Penengah CAS 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4
2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino)piperidine CAS 309956-78-3
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0
Jeneng Kimia | 2-(Chloromethyl)-4-Methylquinazoline |
sinonim | Linagliptin Intermediate A |
Nomer CAS | 109113-72-6 |
Nomer CAT | RF-PI498 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C10H9ClN2 |
Bobot Molekul | 192.64 |
Kapadhetan | 1.251 |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Kuning pucat nganti bubuk coklat pucat |
Identifikasi A | Spektrum IR sampel kudu cocog karo spektrum standar |
Identifikasi B | Wektu penylametan puncak prinsip sampel kudu cocog karo standar |
Kelarutan | Larut ing Methylene Chloride;Ora larut ing banyu |
Kemurnian / Metode Analisis | ≥99,0% (HPLC) |
Titik Lebur | 60,0 kanggo 65,0 ℃ |
Banyu (KF) | ≤0,50% |
Sisa ing Ignition | ≤0,50% |
Zat sing gegandhengan | |
Impurity Tunggal | ≤0,30% |
Total Impurities | ≤1,0% |
Standar Tes | Standar Perusahaan |
Panggunaan | Intermediate kanggo Linagliptin (CAS: 668270-12-0) |
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
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2-(Chloromethyl)-4-Methylquinazoline (CAS: 109113-72-6) digunakake minangka perantara kanggo nyiapake Linagliptin (CAS: 668270-12-0), lan impurities.Linagliptin, sing didol kanthi jeneng merek Tradjenta antara liya, minangka obat sing digunakake kanggo nambani diabetes mellitus jinis 2. Umume kurang disenengi tinimbang metformin lan sulfonylureas minangka perawatan awal.Iki digunakake bebarengan karo olahraga lan diet.Ora dianjurake kanggo diabetes jinis 1.Kerjane kanthi nambah produksi insulin lan nyuda produksi glukagon dening pankreas.Linagliptin disetujoni kanggo panggunaan medis ing Amerika Serikat ing 2011. Linagliptin minangka inhibitor dipeptidyl peptidase-4 (DPP-4) sing selektif kanthi IC50 saka 1 nM sing kuat banget.
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