2-Methyltryptamine CAS 2731-06-8 Kemurnian >99,0% (HPLC) Panobinostat Intermediate Factory Kualitas Tinggi
Pasokan Produsen Kanthi Kualitas Tinggi, Produksi Komersial
Jeneng Kimia: 2-Methyltryptamine CAS: 2731-06-8
Jeneng Kimia | 2-Metiltriptamin |
sinonim | 2-Methylindole-3-Ethylamine;2-(2-Metil-1H-indol-3-yl)etanamine;3-(2-Aminoetil)-2-Methylindole |
Nomer CAS | 2731-06-8 |
Nomer CAT | RF-PI1480 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C11H14N2 |
Bobot Molekul | 174.25 |
Titik Lebur | 106,0 kanggo 110,0 ℃ |
Titik didih | 177 ℃ / 1.5mmHg (lit.) |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Coklat Solid |
Kemurnian / Metode Analisis | > 99,0% (Area HPLC) |
1-HNMR | Konsisten karo Struktur |
Mundhut ing Pangatusan | <1.00% |
Impurity Tunggal | <0,50% |
Total Impurities | <1.00% |
Logam Berat (Pb) | <20 ppm |
Standar Tes | Standar Perusahaan |
Panggunaan | Penengah Farmasi;Panobinostat Intermediate |
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
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2-Methyltryptamine (CAS: 2731-06-8) minangka bahan wiwitan utama ing sintesis Panobinostat (LBH589) (CAS: 404950-80-7).Panobinostat minangka inhibitor kuat kabeh deacetylase histon (HDAC), kanthi nilai Ki antara 0,6 nganti 31 nM kanggo HDAC1-11.Liwat tumindak iki, ndadékaké asetilasi sawetara protèin seluler, sing nyebabake penahanan siklus sel lan apoptosis ing sel kanker.Panobinostat minangka inhibitor HDAC pisanan sing disetujoni dening FDA kanggo perawatan macem-macem myeloma.Panobinostat dipasarake minangka Farydak, digunakake ing kombinasi karo Bortezomib (CAS: 179324-69-7) lan Dexamethasone (CAS: 50-02-2) kanggo nambani myeloma kaping kambuh sawise perawatan sadurunge karo Bortezomib lan immunomodulator.
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