2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0 Kemurnian ≥99,5% (GC) Sitagliptin Fosfat Monohydrate Intermediate
Pasokan Sitagliptin Phosphate Monohydrate Related Intermediate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Asam Trifluorofenilasetat CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Jeneng Kimia | 2,4,5-Asam Trifluorofenilasetat |
Nomer CAS | 209995-38-0 |
Nomer CAT | RF-PI1191 |
Status Simpenan | Ing Simpenan, Skala Produksi Nganti Ton |
Formula Molekul | C8H5F3O2 |
Bobot Molekul | 190.12 |
Titik Lebur | 121,0 kanggo 125,0 ℃ |
Kelarutan | Larut ing Metanol |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Bubuk Putih nganti Putih |
Kemurnian / Metode Analisis | ≥99,5% (GC) |
Kelembapan (KF) | ≤0,50% |
Sisa ing Ignition | ≤0,50% |
Total Impurities | ≤0,50% |
Standar Tes | Standar Perusahaan |
Panggunaan | Intermediate saka Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Paket: Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan.
2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) minangka perantara saka Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9).Sitagliptin Phosphate (STG) digunakake kanggo nambani DM tipe 2 amarga nambah kontrol glikemik kanthi nambah tingkat hormon incretin aktif, GLP-1 (peptida-1) lan GIP (glucose-dependent insulinotropic peptide).Aktivasi incretin kasebut ing sel β-pankreas nyebabake paningkatan tingkat siklik adenosin monofosfat (cAMP) lan kalsium intraselular, kanthi sekresi insulin gumantung glukosa sabanjure (2).Obat hipoglikemik iki kalebu kelas anyar sing diarani inhibitor dipeptidyl peptidase IV.STG disetujoni dening FDA ing 2006.