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3-[3-(Trifluoromethyl)fenil]-1-Propanol CAS 78573-45-2 Cinacalcet Hydrochloride Kemurnian Menengah >99,0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. minangka produsen terkemuka 3-[3-(Trifluoromethyl)fenil]-1-Propanol (CAS: 78573-45-2) kanthi kualitas dhuwur.Ruifu Chemical bisa nyedhiyakake pangiriman ing saindenging jagad, rega kompetitif, jumlah cilik lan akeh sing kasedhiya.Tuku 3-[3-(Trifluoromethyl)fenil]-1-Propanol,Please contact: alvin@ruifuchem.com
| Jeneng Kimia | 3-[3-(Trifluoromethyl)fenil]-1-Propanol |
| sinonim | 3-[3-(Trifluoromethyl)fenil]propanol;3-(3'-Trifluoromethylphenyl)propanol;3-(3-(Trifluoromethyl)fenil)propan-1-ol;3-(Trifluoromethyl)benzena propanol |
| najis | USP Cinacalcet Senyawa Gegandhengan E |
| Status Simpenan | Ing Simpenan, Skala Komersial |
| Nomer CAS | 78573-45-2 |
| Formula Molekul | C10H11F3O |
| Bobot Molekul | 204,19 g / mol |
| Titik didih | 60 ℃ / 1.13mmHg (lit.) |
| Titik Flash | 105 ℃ |
| Suhu panyimpenan | Panggonan Kelangan & Garing |
| COA & MSDS | kasedhiya |
| Babagan | Perantara Farmasi |
| Merk | Kimia Ruifu |
| barang | Standar Inspeksi | Asil |
| Penampilan | Cairan ora ana warna nganti kuning cahya | tundhuk |
| Banyu dening Karl Fischer | <0,50% | 0,07% |
| Kemurnian / Metode Analisis | > 99,0% (HPLC) | 99,60% |
| Indeks bias n20/D | 1.462~1.466 | tundhuk |
| Kapadhetan (20 ℃) | 1.212~1.216 | tundhuk |
| Spektrum Infrared | Konsisten karo Struktur | tundhuk |
| 1 H NMR Spektrum | Konsisten karo Struktur | tundhuk |
| Kesimpulan | Produk wis diuji & tundhuk karo spesifikasi | |
| Aplikasi | Intermediate saka Cinacalcet Hydrochloride (CAS: 364782-34-3) | |
Paket:Botol, tas Aluminium foil, 25kg / Drum Karton, utawa miturut kabutuhan pelanggan.
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing gudang sing adhem lan garing adoh saka bahan sing ora cocog.Nglindhungi saka cahya lan Kelembapan.
Pengiriman:Ngirim menyang donya dening FedEx / DHL Express.Nyedhiyakake pangiriman sing cepet lan dipercaya.
Carane Tuku?Mangga kontakDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Pengalaman 15 Taun?Kita duwe luwih saka 15 taun pengalaman ing Pabrik lan ekspor saka sawetara saka sudhut intermediet pharmaceutical kualitas dhuwur utawa bahan kimia nggoleki.
Pasar Utama?Adol menyang pasar domestik, Amerika Utara, Eropa, India, Korea, Jepang, Australia, lsp.
Kaluwihan?Kualitas unggul, rega terjangkau, layanan profesional lan dhukungan teknis, pangiriman cepet.
KualitasJaminan?Sistem kontrol kualitas sing ketat.Peralatan profesional kanggo analisis kalebu NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Sampel?Umume produk nyedhiyakake conto gratis kanggo evaluasi kualitas, biaya pengiriman kudu dibayar dening pelanggan.
Audit Pabrik?Audit pabrik welcome.Mangga nggawe janjian ing advance.
MOQ?Ora MOQ.pesenan cilik ditrima.
Wektu Pangiriman? Yen ing saham, telung dina pangiriman dijamin.
Transportasi?Miturut Express (FedEx, DHL), dening Air, dening Sea.
Dokumen?Sawise layanan sales: COA, MOA, ROS, MSDS, etc.
Sintesis khusus?Bisa nyedhiyakake layanan sintesis khusus sing cocog karo kabutuhan riset sampeyan.
Syarat-syarat pembayaran?Invoice Proforma bakal dikirim dhisik sawise konfirmasi pesenan, dilampirake informasi bank kita.Pembayaran kanthi T / T (Transfer Telex), PayPal, Western Union, lsp.
3-[3-(Trifluoromethyl)phenyl]-1-Propanol (CAS: 78573-45-2) minangka perantara ing sintesis Cinacalcet Hydrochloride (CAS: 364782-34-3).Cinacalcet minangka entri pisanan ing kelas agen terapeutik anyar sing disebut kalsimimetik.Iki diluncurake minangka perawatan lisan kanggo hiperparatiroidisme sekunder (SHPT) ing pasien karo penyakit ginjel kronis ing dialisis lan kanggo hiperkalsemia ing pasien karo karsinoma paratiroid.SHPT digandhengake karo peningkatan sekresi hormon paratiroid (PTH), sing dipicu dening tingkat kalsium serum sing kurang amarga gagal ginjel mbusak fosfor saka awak lan ora bisa ngasilake jumlah vitamin D sing cukup. Konsekuensi saka tambah PTH kalebu stimulasi aktivitas osteoklastik, resorpsi balung kortikal lan fibrosis sumsum.Sekresi PTH utamane diatur dening reseptor kalsium-sensing (CaR), sing dumunung ing permukaan sel utama kelenjar paratiroid.Calcimimetics ikatan karo CaR lan nambah sensitivitas CaR menyang kalsium ekstraselular, saéngga bisa aktif ing tingkat kalsium serum sing subnormal.Akibaté, ing ngarsane agen kasebut, tingkat kalsium endogen sing kurang ing pasien kanthi gagal ginjal bisa nyebabake efek suppressive ing sekresi PTH.Karsinoma paratiroid uga digandhengake karo tingkat PTH sing dhuwur, sing didorong dening aktivitas kelenjar paratiroid otonom lan banjur nyebabake hiperkalsemia.Sanajan reseksi bedhah minangka terapi utama kanggo ngobati hiperkalsemia ing pasien karsinoma paratiroid, kalsimimetik nawakake alternatif non-bedah kanggo pasien gagal paratiroidektomi, karsinoma paratiroid metastatik, utawa risiko bedah dhuwur.
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