3-Ethynylaniline CAS 54060-30-9 Kemurnian >99,0% (GC) Erlotinib Hydrochloride Intermediate
Produsen utama lan pemasok Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-siji CAS 179688-29-0
Please contact: alvin@ruifuchem.com
Jeneng Kimia | 3-Ethynylaniline |
sinonim | 3-Aminophenylacetylene |
Nomer CAS | 54060-30-9 |
Nomer CAT | RF-PI2241 |
Status Simpenan | Ing Simpenan, Kapasitas Produksi 50MT / Wulan |
Formula Molekul | C8H7N |
Bobot Molekul | 117.15 |
Sensitif | Sensitif Udara, Sensitif Cahya |
Titik didih | 120 ℃ / 20 mmHg |
Kelarutan banyu | Ora larut ing banyu |
Merk | Kimia Ruifu |
Item | Spesifikasi |
Penampilan | Cairan Cairan Kuning nganti Coklat |
Kemurnian / Metode Analisis | > 99,0% (GC) |
Banyu dening Karl Fischer | <0,50% |
Sisa ing Ignition | <0,20% |
Total Impurities | <1.00% |
Gravitasi spesifik (20/20 ℃) | 1.041~1.048 |
Indeks bias n20/D | 1.614~1.6195 |
Spektrum Infrared | Conforms kanggo Struktur |
Proton NMR Spectrum | Conforms kanggo Struktur |
Test Standar | Standar Perusahaan |
Panggunaan | Pharmaceutical Intermediate;Erlotinib Hydrochloride Intermediate |
Paket: Botol Fluorinated, 25kg / Drum, utawa miturut kabutuhan pelanggan
Kondisi panyimpenan:Simpen ing wadhah sing disegel ing papan sing adhem lan garing;Nglindhungi saka cahya lan Kelembapan
3-Ethynylaniline, uga dikenal minangka 3-Aminophenylacetylene (CAS: 54060-30-9) digunakake minangka penengah pharmaceutical.3-Ethynylaniline minangka perantara saka Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochloride minangka inhibitor tirosin kinase molekul cilik sing tumindak kanthi reversibel ing reseptor pertumbuhan epidermis, hidroklorida saka erlotinib, obat sing ditargetake molekuler.US Food and Drug Administration (FDA) wis nyetujoni erlotinib (Tarceva) digabungake karo gemcitabine minangka perawatan lini pertama kanggo kanker pankreas sing maju lan metastatik lokal.Utamane digunakake minangka perawatan baris kapindho utawa katelu kanggo kanker paru-paru sel non-cilik (NSCLC) maju utawa metstatic lokal lan minangka perawatan kanggo kanker pankreas.Iki digunakake minangka inhibitor tirosin kanggo perawatan NSCLC.Erlotinib Hydrochloride, quinazoline asalé saka inhibitor molekul cilik saka epidermal growth receptor (EDGFR) tyrosine kinase, disetujoni ing November, 2004, kanggo perawatan kanker paru-paru non-sel cilik metastatik lanjut utawa metastatik.